The current preliminary data from Africa do not show greater clinical severity in confirmed cases, according to the European Centre for Disease Control (ECDC). The ECDC warned of the unknowns amid growing expert concerns about the virulence of mpox's new variant, Clade 1b. While it has been stated that Clade 1 is more fatal than Clade 2, the current situation does not support this claim conclusively, leaving much information still to be clarified.
According to virologist Jose Antonio Lopez Guerrero, the pressing issue isn't just the behavior of the new mpox variant, but also the environmental conditions surrounding its transmission. The complexity of the context in the Democratic Republic of the Congo—the military conflicts and dire socio-economic conditions—makes it difficult to ascertain true transmission dynamics. Experts are urging a reassessment of assumptions regarding this strain's danger level and transmission capabilities.
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