Lugo allowed four hits - all singles - in his third straight win, striking out four and walking one. Kansas City improved to 5-0 against Chicago this season.
The Royals have allowed a major league-low 48 runs in their 11-6 start, while the White Sox have scored the lowest in the big leagues with 34 runs - highlighting Kansas City's strong pitching and Chicago's struggling offense.
Nastrini made his MLB debut, retiring his first 11 batters before giving up a homer to Pasquantino. Despite a solid 5-inning performance, the White Sox offense fell short.
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