The hard-throwing, 24-year-old right-hander threw 66 1/3 innings for the White Sox last season to the tune of a 3.39 ERA, 1.296 WHIP and 2.56 FIP, with 66 strikeouts to 17 walks.
Add Santos to Andrés Muñoz and Matt Brash at the back end of Seattle's bullpen, and that's a dominant trio for opposing batters to worry about.
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