Seth Lugo pitched seven crisp innings, allowing only four singles in his third straight win, striking out four and walking one.
Kansas City Royals have allowed a major league-low 48 runs in their 11-6 start, while the White Sox have scored the lowest total of 34 runs.
Vinnie Pasquantino homered in the fourth inning, and Kyle Isbel contributed with an RBI single in the fifth for the Royals' two runs against the White Sox.
White Sox right-hander Nick Nastrini had a decent major league debut, allowing 2 runs over 5 innings, but he was outdueled by Seth Lugo's strong pitching performance.
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