Boston's innovation economy hits a new milestone in global rankings

"While Boston has long been an innovation hub, this year it has taken that leadership to a whole new level. From life sciences and RNA therapeutics to consumer technology, Boston's innovation ecosystem is firing on all cylinders, and it shows the power of bringing together world-class research institutions, deep venture capital networks, and entrepreneurial ambition in a community."

"Orna Therapeutics, which is developing treatments that use circular RNA and special lipid particles to help the body make its own disease-fighting cell therapies, was acquired last month by Eli Lilly for $2.4 billion. Eli Lilly also made the list, though its headquarters are in Indianapolis."

"Flagship Pioneering, which launched in 2000, has fostered more than 100 scientific ventures and manages $14 billion in assets."

Boston achieved its highest representation on LexisNexis's Top 100 Global Innovators list with five companies, including returning honorees Alnylam Pharmaceuticals and Moderna, plus three first-time honorees: Flagship Pioneering, Orna Therapeutics, and SharkNinja. This recognition highlights Boston's strength as an innovation hub combining world-class research institutions, venture capital networks, and entrepreneurial talent. The achievement comes despite industry challenges including federal spending cuts, new policies, tariffs, and higher interest rates. Orna Therapeutics, developing circular RNA treatments, was recently acquired by Eli Lilly for $2.4 billion. Flagship Pioneering has fostered over 100 scientific ventures managing $14 billion in assets, while SharkNinja gained prominence through its viral Creami frozen treat maker.

Read at Boston.com