Using AI to repurpose existing drugs for treatment of rare diseases - Harvard Gazette
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from Harvard Gazette1 month ago
"With this tool we aim to identify new therapies across the disease spectrum but when it comes to rare, ultrarare, and neglected conditions, we foresee this model could help close, or at least narrow, a gap that creates serious health disparities," said lead researcher Marinka Zitnik, assistant professor of biomedical informatics in the Blavatnik Institute at HMS.
Harvard Gazettehttps://news.harvard.edu/gazette/story/2024/09/using-ai-to-repurpose-existing-drugs-for-treatment-of-rare-diseases/
The AI model, called TxGNN, is the first one developed specifically to identify drug candidates for rare diseases and conditions with no treatments.
Harvard Gazettehttps://news.harvard.edu/gazette/story/2024/09/using-ai-to-repurpose-existing-drugs-for-treatment-of-rare-diseases/
Developing new medicines represents a daunting challenge, but a new artificial intelligence tool can propel the discovery of new therapies from existing medicines, offering hope for patients with rare and neglected conditions and for the clinicians who treat them.
Harvard Gazettehttps://news.harvard.edu/gazette/story/2024/09/using-ai-to-repurpose-existing-drugs-for-treatment-of-rare-diseases/
The researchers have made the tool available for free and want to encourage clinician-scientists to use it in their search for new therapies, especially for conditions with no or with limited treatment options.
Harvard Gazettehttps://news.harvard.edu/gazette/story/2024/09/using-ai-to-repurpose-existing-drugs-for-treatment-of-rare-diseases/
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#rare-diseases #drug-discovery #healthcare-innovation #health-disparities
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