"A new report from OpenAI and a group of outside scientists shows how GPT-5, the company's latest AI large language model (LLM), can help with research from black holes to cancerfighting cells to math puzzles. Each chapter in the paper offers case studies: a mathematician or a physicist stuck in a quandary, a doctor trying to confirm a lab result. They all ask GPT-5 for help. Sometimes the LLM gets things wrong."
"Sometimes it finds a faster route to an already known result. But other times, with careful human guidance, it helps push the boundaries of what was previously known. In one experiment involving how waves behave around black holes, GPT-5 worked through the math to independently produce results that had previously been shown to be correct, showing it was capable of doing this level of scientific calculation."
GPT-5 assisted research across physics, mathematics, nuclear fusion, and immunology by working through complex calculations, proposing models, and interpreting experimental data. In a black hole experiment the model independently derived previously validated mathematical results. In a nuclear fusion project it developed an accelerating model. In immunology work GPT-5 interpreted data in agreement with laboratory confirmations and generated experimentally testable hypotheses. The model can compress coding and reasoning tasks from days or months into minutes, enabling faster iteration. The model is not infallible: it sometimes produces incorrect outputs and benefits from careful human guidance to ensure scientific validity.
Read at www.scientificamerican.com
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