"The original name for estrogen was adipin, so called because it was known to make you fat, as in adipose (fat) tissue. In the mid-'50s, when the drug industry started pushing synthetic estrogens, this knowledge faded from memory. One of the most infamous early synthetic estrogens prescribed was diethylstilbestrol (DES), which caused fetal malformations and deaths, and cancers in the mothers who took it."
""Even mainstream doctors will admit that there is this thing called estrogen receptor-positive breast cancer," Georgi says. "The role of estrogen there is well known. Nobody's denying it, but the story has always been, it's a localized-only effect. It's a tissue-specific effect. If you look at the estrogen levels of menopausal women ... it's undetectable. However, if you take a tissue biopsy from the tumor or the breast tissue around it, you'll see that estrogen levels are sky-high there.""
Estrogen and serotonin, often regarded as beneficial, can produce serious adverse effects when elevated. Estrogen promotes fat accumulation and functions as a carcinogen; synthetic estrogenic compounds such as diethylstilbestrol (DES) caused fetal malformations, maternal cancers, and were later withdrawn. Steroidal estrogens used in hormone replacement therapy and oral contraceptives are listed as known human carcinogens by the NIH. Estrogen concentrations can be low in circulation yet very high within tumor tissue, contributing to estrogen receptor-positive breast cancer. Pharmaceutical framing of depression as low-serotonin overlooks serotonin's potential harms when levels are excessive.
Read at Natural Health News
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