Outro provides a unique approach to tapering medications, specifically antidepressants, by utilizing a hyperbolic tapering strategy. This method involves decreasing medication doses at a gradually slowing rate, producing minuscule doses through partnerships with compounding pharmacies. Horowitz, a key figure in this initiative, faced significant challenges while discontinuing antidepressants himself, which led him to advocate for better tapering protocols. His experience has informed the development of new standards, aiming to assist North American patients effectively while keeping them on custom-compounded drugs prescribed by Outro clinicians.
Unlike a linear taper that reduces medication by the same amount, a hyperbolic taper gradually slows the rate of reduction, resulting in very small and spaced-out doses.
Horowitz, a leading expert on medication tapering, initiated research after his own distressing experience withdrawing from antidepressants, leading him to advocate for improved guidelines.
Horowitz's withdrawal symptoms were so severe that he had to move back in with his parents, highlighting the challenges of discontinuing antidepressants without proper support.
Outro aims to apply Horowitz's tapering methods to help North American patients, offering custom compounded drugs from partner pharmacies to aid in medication cessation.
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