
GLP-1 agonists are medications used to manage blood sugar levels in people with type 2 diabetes. Some GLP-1s are also used for obesity because they increase fullness and reduce the desire to eat as often or as much. The drugs work by mimicking the naturally occurring hormone GLP-1, which stimulates insulin secretion. Insulin helps the body use sugars from food for energy, lowering blood sugar levels. GLP-1 also blocks glucagon secretion, a hormone that raises blood sugar when needed, and slows digestion. These effects can contribute to reduced food intake and weight loss, while metabolic dysfunction and obesity remain major global health concerns linked to cardiovascular disease, diabetes, and cancer.
"GLP-1s describe a class of medication commonly used to manage blood sugar levels via injection for those with Type 2 diabetes. Recently, however, some GLP-1s have also been widely used to treat obesity, as they tend to help people feel fuller for longer, thereby reducing their desire to eat as much or as often as they once did. Over time, this decrease in food intake may contribute to weight loss in some people."
"These outcomes are made possible because GLP-1 agonists, the medication, mimic the naturally occurring hormone GLP-1, a peptide the body uses to stimulate insulin secretion. Since insulin allows the body to use sugars from food for energy, its presence reduces the amount of sugar in the bloodstream. With less insulin comes a higher concentration of blood sugar, leading to diabetes."
"GLP-1 also blocks the secretion of glucagon, a hormone the body uses to raise its blood sugar levels if necessary, and slows digestion. While GLP-1s, as a class of medications, are fairly well understood by this point, their roles in hormone optimization and their"
Read at The Village Voice
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