After closest challengers AC Milan drew 3-3 at Sassuolo earlier on, Inter could have moved 16 points ahead with six fixtures left and they led at the interval courtesy of Marcus Thuram's early strike.
The stalemate might just be a mere hiccup for Inter, who can seal a first Scudetto in three years by beating city rivals Milan next Monday although twice squandering one-goal leads will doubtless frustrate head coach Simone Inzaghi.
But the visiting backline was split open as Matteo Darmian slid through to Alexis Sanchez, who hared to keep the ball in play and his cutback was tucked away by the onrushing Thuram after 12 minutes.
A speculative long ball forward from Adam Obert was brought down by Luvumbo with his knee and led to Shomurodov lashing low beyond Sommer from the edge of the area in the 64th minute.
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