Medicine
fromNature
1 week agoThe misunderstood sex chromosome: how X affects your health
Statins cause more muscle pain in women due to a gene on the X chromosome, not sex hormones, with potential mitigation through fish oil.
Other than the well-known risks around muscle pain and diabetes, only four of 66 other statin side-effects listed on labels liver test changes, minor liver abnormalities, urine changes and tissue swelling are supported by evidence. And the risks are very small, according to the systematic review and meta-analysis published in the Lancet. Statins have been used by hundreds of millions of people worldwide over the last three decades and are proven to reduce heart attacks, strokes and cardiovascular deaths.
In 2004-2005, new regulations mandated full disclosure of clinical trial data, allowing independent researchers to analyze statins' primary data, revealing exaggerated benefits.