#side-effects

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#clinical-trials
from Fortune Europe
1 month ago
Medicine

Roche stock drops 5% after report its Wegovy challenger is causing patients to vomit

Roche's obesity pill faces challenges with side effects that may impact its competitive edge in the weight-loss pharmaceutical market.

Rethinking the Burden of Cancer Treatments' Side Effects - News Center

Even mild and moderate side effects can lead to cancer patients discontinuing treatment.
Patient-reported perspectives on side effects are crucial for understanding treatment tolerability.

Men with advanced prostate cancer missing months of therapy' amid medication shortage

Doctors across the United States who treat people with advanced prostate cancer can't find supplies of a medicine that may help them live longer.Pluvicto, a drug to treat metastatic castration-resistant prostate cancer, also known as mCRPC, is in such short supply that its maker, Novartis, said it cannot allow further supply until it can produce more of the drug.

Roche stock drops 5% after report its Wegovy challenger is causing patients to vomit

Roche's obesity pill faces challenges with side effects that may impact its competitive edge in the weight-loss pharmaceutical market.

Rethinking the Burden of Cancer Treatments' Side Effects - News Center

Even mild and moderate side effects can lead to cancer patients discontinuing treatment.
Patient-reported perspectives on side effects are crucial for understanding treatment tolerability.

Men with advanced prostate cancer missing months of therapy' amid medication shortage

Doctors across the United States who treat people with advanced prostate cancer can't find supplies of a medicine that may help them live longer.Pluvicto, a drug to treat metastatic castration-resistant prostate cancer, also known as mCRPC, is in such short supply that its maker, Novartis, said it cannot allow further supply until it can produce more of the drug.
moreclinical-trials
#functional-programming

What is referential transparency in essence?

Referential transparency enables replacing expressions with values without changing program behavior, crucial for functional programming.

Pure Functions: They Cannot Lie (Scala 3 Video)

Pure function signatures in Functional Programming are essential as they provide clarity on the function's behavior, unlike in Object-Oriented Programming.

What is referential transparency in essence?

Referential transparency enables replacing expressions with values without changing program behavior, crucial for functional programming.

Pure Functions: They Cannot Lie (Scala 3 Video)

Pure function signatures in Functional Programming are essential as they provide clarity on the function's behavior, unlike in Object-Oriented Programming.
morefunctional-programming

35 Products To Help You Become The Carry-On-Only Traveler You've Always Dreamed Of Being This Fall

Independent selections by editors ensure quality recommendations.
Gliding through travel with curated choices enhances the experience.
from ScienceDaily
1 month ago

New study provides insight to why COVID vaccines hit some harder than others

Factors such as stress, exercise, and hormonal birth control may influence perceived side effects of the COVID-19 vaccine.

CBD side effects: Is it safe and what are the risks?

CBD is a non-psychoactive compound derived from cannabis, valued for its potential health benefits.

EU regulator rejects Alzheimer's drug lecanemab

The European Medicines Agency (EMA) rejected a license for an Alzheimer's treatment due to serious side effects outweighing benefits.
#chemotherapy
from Nature
5 months ago

How antibody-drug conjugates aim to take down cancer

Chemotherapy's side effects lead to discontinuation, pushing for palliative care.
from Cbsnews
7 months ago

Princess Kate revealed she is undergoing treatment for a cancer diagnosis. What is preventative chemotherapy?

Preventative chemotherapy reduces the chance of cancer returning after surgery.
Adjuvant chemotherapy aims to eliminate microscopic cancer cells to prevent growth.

How antibody-drug conjugates aim to take down cancer

Chemotherapy's side effects lead to discontinuation, pushing for palliative care.

Princess Kate revealed she is undergoing treatment for a cancer diagnosis. What is preventative chemotherapy?

Preventative chemotherapy reduces the chance of cancer returning after surgery.
Adjuvant chemotherapy aims to eliminate microscopic cancer cells to prevent growth.
morechemotherapy

Almost 80 legal cases arise from alleged side-effects of Covid vaccines

Health Minister working on compensation scheme for Covid-19 vaccine side-effects.
#weight-loss

The Longest Clinical Trial Yet Of Blockbuster Weight Loss Drug Wegovy Reveals Significant Side Effects

GLP-1 agonists like Wegovy show significant weight loss and may have long-lasting effects, but concerns exist regarding side effects.

'Ozempic makes me feel full for longer; weight has come off for the first time in years' - Wexford woman's weight-loss journey

Ozempic helped the woman feel full for longer and reduced cravings, leading to weight loss.
The woman experienced side effects such as constipation and nausea, but managed them with guidance from her healthcare team.

The Longest Clinical Trial Yet Of Blockbuster Weight Loss Drug Wegovy Reveals Significant Side Effects

GLP-1 agonists like Wegovy show significant weight loss and may have long-lasting effects, but concerns exist regarding side effects.

'Ozempic makes me feel full for longer; weight has come off for the first time in years' - Wexford woman's weight-loss journey

Ozempic helped the woman feel full for longer and reduced cravings, leading to weight loss.
The woman experienced side effects such as constipation and nausea, but managed them with guidance from her healthcare team.
moreweight-loss

10 Facts About GLP-1 Weight Loss Medications Your Doctor Might Not Mention

Needle phobia can impact GLP-1 therapy, while managing feeling of fullness is crucial for successful treatment.
#public-health

The Side Effects of Covid Vaccines

The benefits of Covid vaccines outweigh the downsides despite some reported serious side effects.

Thousands Believe Covid Vaccines Harmed Them. Is Anyone Listening?

Covid-19 vaccines, while crucial for preventing hospitalizations and deaths, can also result in rare but serious side effects, leading to significant long-term consequences for some individuals.

The Side Effects of Covid Vaccines

The benefits of Covid vaccines outweigh the downsides despite some reported serious side effects.

Thousands Believe Covid Vaccines Harmed Them. Is Anyone Listening?

Covid-19 vaccines, while crucial for preventing hospitalizations and deaths, can also result in rare but serious side effects, leading to significant long-term consequences for some individuals.
morepublic-health

Taking Multiple Medications? You May Need to Scale Back.

Polypharmacy is common among older adults, increasing risks of side effects, drug interactions, memory decline, falls, hospitalization, and unnecessary medications due to lack of coordination among medical providers.

Hormonal Birth Control Doesn't Deserve Its Bad Reputation

Two-thirds of U.S. women of reproductive age use hormonal contraception methods with high efficacy rates.
Concerns about side effects lead to some women quitting hormonal birth control and opting for less effective natural methods.

Safety fears over asthma drug after young children suffer severe side effects

Families report severe side effects from montelukast, including night terrors and suicidal behavior.
Campaigners demand more prominent warnings, stricter controls, and support for those affected by montelukast.

Understanding React useEffect - SitePoint

The useEffect hook in React enables side effect handling in functional components.
The dependency array in useEffect controls when the effect runs based on specified variables.

Primer on Python Decorators - Real Python

Functions in Python can have side effects and return values based on given arguments.
Functions in Python can be treated as first-class objects, meaning they can be passed as arguments and used like any other object.

As cancer treatment advances, patients and doctors push back against drugs' harsh side effects

Patients and doctors are advocating for a change in how new cancer drugs are tested to minimize harsh side effects.
Cancer drug development has traditionally focused on finding the maximum tolerated dose, but this approach may not be necessary for newer, more targeted drugs.

Dr. Sanjay Gupta answers your questions about new weight loss drugs

Ozempic, Wegovy, and Mounjaro are weight loss drugs that have potential side effects.
It is important to consult with a healthcare professional before starting or stopping these medications.
#fda

Drugs like Ozempic and Wegovy Show No Link to Suicide, FDA Says

The FDA has conducted a preliminary review of side effects from popular drugs used to treat diabetes and obesity and found no link with suicidal thoughts or actions.
The agency will continue to investigate reports regarding more than a dozen drugs, including Ozempic, Wegovy, and Mounjaro.

Drugs like Ozempic and Wegovy Show No Link to Suicide, FDA Says

The FDA has conducted a preliminary review of side effects from popular drugs used to treat diabetes and obesity and found no link with suicidal thoughts or actions.
The agency will continue to investigate reports regarding more than a dozen drugs, including Ozempic, Wegovy, and Mounjaro.

Drugs like Ozempic and Wegovy Show No Link to Suicide, FDA Says

The FDA has conducted a preliminary review of side effects from popular drugs used to treat diabetes and obesity and found no link with suicidal thoughts or actions.
The agency will continue to investigate reports regarding more than a dozen drugs, including Ozempic, Wegovy, and Mounjaro.

Drugs like Ozempic and Wegovy Show No Link to Suicide, FDA Says

The FDA has conducted a preliminary review of side effects from popular drugs used to treat diabetes and obesity and found no link with suicidal thoughts or actions.
The agency will continue to investigate reports regarding more than a dozen drugs, including Ozempic, Wegovy, and Mounjaro.
morefda

Drugs like Ozempic and Wegovy Show No Link to Suicide, FDA Says

The FDA has conducted a preliminary review of side effects from popular drugs used to treat diabetes and obesity and found no link with suicidal thoughts or actions.
The agency will continue to investigate reports regarding more than a dozen drugs, including Ozempic, Wegovy, and Mounjaro.

5 Common mistakes when using useEffect in React

1. useEffect requires specifying dependencies to ensure side effects run when necessary.
2. Overusing and improperly organizing useEffect blocks can lead to difficult-to-maintain code.
#React

5 Common mistakes when using useEffect in React

1. useEffect requires specifying dependencies to ensure side effects run when necessary.
2. Overusing and improperly organizing useEffect blocks can lead to difficult-to-maintain code.

5 Common mistakes when using useEffect in React

1. useEffect requires specifying dependencies to ensure side effects run when necessary.
2. Overusing and improperly organizing useEffect blocks can lead to difficult-to-maintain code.

5 Common mistakes when using useEffect in React

1. useEffect requires specifying dependencies to ensure side effects run when necessary.
2. Overusing and improperly organizing useEffect blocks can lead to difficult-to-maintain code.

5 Common mistakes when using useEffect in React

1. useEffect requires specifying dependencies to ensure side effects run when necessary.
2. Overusing and improperly organizing useEffect blocks can lead to difficult-to-maintain code.
moreReact
#side effects

Why Women Hate the Pill | The Walrus

Teenagers are often prescribed birth control to avoid pregnancy, but the side effects can be severe and vary from person to person.
Certain contraceptives can cause health problems such as high inflammation markers and cortisol levels.

They thought I had cancer': painkiller banned in UK linked to Britons' deaths in Spain

A patients group representing British victims has launched legal action against the Spanish government over the side effects of a popular painkiller.
The drug, known as Nolotil in Spain, is banned in several countries due to its potentially fatal side effects.
The patients group is demanding an investigation into the drug and new controls.

Is Novavax, the latecomer COVID vaccine, worth the wait?

People with autoimmune diseases like arthritis are seeking out the Novavax COVID-19 vaccine due to potential side effects from mRNA vaccines.
Data suggests that people who received the Novavax vaccine had fewer temporary reactions compared to those who got mRNA boosters.
Biologists are also interested in Novavax due to its unique technology.

Is Novavax, the latecomer COVID vaccine, worth the wait?

People with autoimmune diseases like arthritis are seeking out the Novavax COVID-19 vaccine due to potential side effects from mRNA vaccines.
Data suggests that people who received the Novavax vaccine had fewer temporary reactions compared to those who got mRNA boosters.
Biologists are also interested in Novavax due to its unique technology.

Why Women Hate the Pill | The Walrus

Teenagers are often prescribed birth control to avoid pregnancy, but the side effects can be severe and vary from person to person.
Certain contraceptives can cause health problems such as high inflammation markers and cortisol levels.

They thought I had cancer': painkiller banned in UK linked to Britons' deaths in Spain

A patients group representing British victims has launched legal action against the Spanish government over the side effects of a popular painkiller.
The drug, known as Nolotil in Spain, is banned in several countries due to its potentially fatal side effects.
The patients group is demanding an investigation into the drug and new controls.

Is Novavax, the latecomer COVID vaccine, worth the wait?

People with autoimmune diseases like arthritis are seeking out the Novavax COVID-19 vaccine due to potential side effects from mRNA vaccines.
Data suggests that people who received the Novavax vaccine had fewer temporary reactions compared to those who got mRNA boosters.
Biologists are also interested in Novavax due to its unique technology.

Is Novavax, the latecomer COVID vaccine, worth the wait?

People with autoimmune diseases like arthritis are seeking out the Novavax COVID-19 vaccine due to potential side effects from mRNA vaccines.
Data suggests that people who received the Novavax vaccine had fewer temporary reactions compared to those who got mRNA boosters.
Biologists are also interested in Novavax due to its unique technology.
moreside effects
#people

Experimental Alzheimer's drug slows cognitive declines in large trial, drugmaker Eli Lilly says

An experimental Alzheimer's medication slowed declines in patients' ability to think clearly and perform daily tasks by more than a third in a large clinical trial, drugmaker Eli Lilly said Wednesday.Based on the results, in people with early symptomatic Alzheimer's disease, Lilly said it plans to file for approval from the US Food and Drug Administration by the end of June.

Gene therapy for muscular dystrophy stirs hopes and controversy

Susan and Chris Finazzo have enrolled their sons Dylan and Chase in a study of gene therapy for Duchenne muscular dystrophy.The experimental treatment is still being studied but researchers hope it may help prevent the devastating effects of the disease.Natalia de la Rosa Reyes/Susan Finazzo When Chase Finazzo was just a few years old, his parents noticed Chase was pretty clumsy.

New drugs promising weight loss are available: What you need to know | amNewYork

Obesity is a major and growing problem around the world, but especially in the U.S., where more than 40% of adults and about 20% of children now meet the criteria for what doctors say has become an intractable chronic disease.Rates of the disease have soared in recent decades, spurred by the complex interaction of genes that make people more likely to store food as fat, a food system that provides easy and cheap access to processed treats explicitly designed to be overconsumed, and social settings that limit access to healthy options and exercise for many people.

What to know about prescription drugs promising weight loss

Obesity is a major and growing problem around the world, but especially in the U.S., where more than 40% of adults and about 20% of children now meet the criteria for what doctors say has become an intractable chronic disease.Rates of the disease have soared in recent decades, spurred by the complex interaction of genes that make people more likely to store food as fat, a food system that provides easy and cheap access to processed treats explicitly designed to be overconsumed, and social settings that limit access to healthy options and exercise for many people.

Psychosocial Therapy: Its Types, Examples and Why Is It Used?

Some people find it very difficult to perform everyday social activities and behaviors.These people feel anxious and nervous when in a public setting and cannot be their true selves.You must have noticed some people are always running away from a social situation.Most people who do that struggle with anxiety or anxiety-related disorder.

My contraceptive pill nearly killed me': Woman's warning after suffering stroke

Only after having this could I move on, she said.Holly McComish was just 25 years old when she had a stroke that almost killed her.Doctors at the hospital told her to immediately stop taking the contraceptive pill she had been prescribed two months earlier.Having been prescribed the pill over the phone and not even been given a pamphlet laying out the risks and side effects associated with taking it, Ms McComish said she was unaware of the pill's more serious potential effects.

Experimental Alzheimer's drug slows cognitive declines in large trial, drugmaker Eli Lilly says

An experimental Alzheimer's medication slowed declines in patients' ability to think clearly and perform daily tasks by more than a third in a large clinical trial, drugmaker Eli Lilly said Wednesday.Based on the results, in people with early symptomatic Alzheimer's disease, Lilly said it plans to file for approval from the US Food and Drug Administration by the end of June.

Gene therapy for muscular dystrophy stirs hopes and controversy

Susan and Chris Finazzo have enrolled their sons Dylan and Chase in a study of gene therapy for Duchenne muscular dystrophy.The experimental treatment is still being studied but researchers hope it may help prevent the devastating effects of the disease.Natalia de la Rosa Reyes/Susan Finazzo When Chase Finazzo was just a few years old, his parents noticed Chase was pretty clumsy.

New drugs promising weight loss are available: What you need to know | amNewYork

Obesity is a major and growing problem around the world, but especially in the U.S., where more than 40% of adults and about 20% of children now meet the criteria for what doctors say has become an intractable chronic disease.Rates of the disease have soared in recent decades, spurred by the complex interaction of genes that make people more likely to store food as fat, a food system that provides easy and cheap access to processed treats explicitly designed to be overconsumed, and social settings that limit access to healthy options and exercise for many people.

What to know about prescription drugs promising weight loss

Obesity is a major and growing problem around the world, but especially in the U.S., where more than 40% of adults and about 20% of children now meet the criteria for what doctors say has become an intractable chronic disease.Rates of the disease have soared in recent decades, spurred by the complex interaction of genes that make people more likely to store food as fat, a food system that provides easy and cheap access to processed treats explicitly designed to be overconsumed, and social settings that limit access to healthy options and exercise for many people.

Psychosocial Therapy: Its Types, Examples and Why Is It Used?

Some people find it very difficult to perform everyday social activities and behaviors.These people feel anxious and nervous when in a public setting and cannot be their true selves.You must have noticed some people are always running away from a social situation.Most people who do that struggle with anxiety or anxiety-related disorder.

My contraceptive pill nearly killed me': Woman's warning after suffering stroke

Only after having this could I move on, she said.Holly McComish was just 25 years old when she had a stroke that almost killed her.Doctors at the hospital told her to immediately stop taking the contraceptive pill she had been prescribed two months earlier.Having been prescribed the pill over the phone and not even been given a pamphlet laying out the risks and side effects associated with taking it, Ms McComish said she was unaware of the pill's more serious potential effects.
morepeople

Amgen Scores Partial Victory in Efforts to Maintain OTEZLA Exclusivity

By Chris Holman
Amgen Inc. v. Sandoz Inc., 2023 WL 2994166, - 4th - (Fed.Cir.Apr. 19, 2023)
In 2019, Amgen acquired worldwide rights to apremilast (OTEZLA) from Celgene $13.4 billion in cash, in connection with Celgene's merger with Bristol-Myers Squibb.Apremilast was the only oral, non-biologic treatment for psoriasis and psoriatic arthritis, and in 2020 apremilast generated $2.2 billion for Amgen.

Write Better CSS By Borrowing Ideas From JavaScript Functions - Smashing Magazine

Many problems with website layouts, such as unwanted side effects, painful updates, and brittle code, happen when we don't write CSS with the same care we'd use when writing a JavaScript function.Let's look at how we can borrow best practices and ideas from writing good JavaScript functions for writing CSS.
#information

Pedro Pascal's Starbucks Order Has Nearly 400 Mg Of Caffeine

When Starbucks recently released its new spring menu, the coffee chain must have somehow forgotten to add the "Pedro Pascal" to the menu.In case you missed it, the The Last of Us star's highly caffeinated drink is blowing up on TikTok.The internet was made aware of actor Pedro Pascal's Starbucks order thanks to a chance encounter with a fan.

How to Convert React Components from Class to Functional with Hooks

In React 16.8, hooks are a brand-new feature.They provide state and other React capabilities without the need for class creation.With React 16.7, we can now convert class-based components to functional components using the new React Hooks.This enables us to use the benefits of both types of components in one project, which is great!

Dr. Michael Dattoli: Changing the Face of P.C Treatment

Dr. Michael Dattoli is revolutionizing the way prostate cancer is treated, giving hope to patients and their families who have been affected by this disease.With his unique approach to treatment, He has achieved remarkable success in treating prostate cancer with minimal side effects and improved patient outcomes.

Pedro Pascal's Starbucks Order Has Nearly 400 Mg Of Caffeine

When Starbucks recently released its new spring menu, the coffee chain must have somehow forgotten to add the "Pedro Pascal" to the menu.In case you missed it, the The Last of Us star's highly caffeinated drink is blowing up on TikTok.The internet was made aware of actor Pedro Pascal's Starbucks order thanks to a chance encounter with a fan.

How to Convert React Components from Class to Functional with Hooks

In React 16.8, hooks are a brand-new feature.They provide state and other React capabilities without the need for class creation.With React 16.7, we can now convert class-based components to functional components using the new React Hooks.This enables us to use the benefits of both types of components in one project, which is great!

Dr. Michael Dattoli: Changing the Face of P.C Treatment

Dr. Michael Dattoli is revolutionizing the way prostate cancer is treated, giving hope to patients and their families who have been affected by this disease.With his unique approach to treatment, He has achieved remarkable success in treating prostate cancer with minimal side effects and improved patient outcomes.
moreinformation
#application

Building a Custom React Hook for Data Fetching

React hooks have become very popular among React developers in recent times.One of the most useful hooks is the useEffect() hook.This hook allows us to perform side effects, such as data fetching, in functional components.In this article, we will explore how to build a custom React hook for data fetching using the useEffect() hook.

React Server Components: Embrace the Future of Web Development

React Server Components (RSC) have burst onto the web development scene, offering a new and exciting way to build modern, efficient, and scalable applications.This innovation seeks to address the limitations of traditional client-side rendering, paving the way for a more performant and dynamic user experience.

Building a Custom React Hook for Data Fetching

React hooks have become very popular among React developers in recent times.One of the most useful hooks is the useEffect() hook.This hook allows us to perform side effects, such as data fetching, in functional components.In this article, we will explore how to build a custom React hook for data fetching using the useEffect() hook.

React Server Components: Embrace the Future of Web Development

React Server Components (RSC) have burst onto the web development scene, offering a new and exciting way to build modern, efficient, and scalable applications.This innovation seeks to address the limitations of traditional client-side rendering, paving the way for a more performant and dynamic user experience.
moreapplication

Johns Hopkins study highlights promise of IV mistletoe extract for cancer therapy

Angela Roberts | The Baltimore Sun Ivelisse Page already had 15 inches of her colon and 28 lymph nodes removed to treat her colon cancer, but in the winter of 2008 she received more devastating news.The cancer had spread to her liver.Page's doctor, Dr. Luis Diaz an oncologist at the Memorial Sloan Kettering Cancer Center in New York and professor at the Johns Hopkins University School of Medicine gave her an 8% chance of living for more than two years.
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