Investigators found FOXC1 and FOXC2 genes regulate retinal angiogenesis and impaired gene expression inhibits mTOR signaling pathway crucial for cellular growth.
FOXC1 was identified as essential for revascularization in pathological retinal angiogenesis, highlighting potential therapeutic implications.
#genetic-mechanisms #retinal-vascular-disease #angiogenesis #mtor-signaling-pathway #retinopathy-of-prematurity
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