#striatum

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#parkinsons-disease #levodopa-induced-dyskinesia #aberrant-learning #motor-timing #cortico-basal-ganglia
Medicine
fromNews Center
3 days ago

Targeting Aberrant Learning May Improve Parkinson's Treatment - News Center

Targeting striatal neuronal signaling that drives aberrant learning can improve levodopa efficacy and reduce levodopa-induced dyskinesia in late-stage Parkinson's disease.
Science
fromwww.nature.com
1 month ago

Integrator dynamics in the cortico-basal ganglia loop for flexible motor timing

Striatal inhibition rewinds the neural timer while frontal cortical inhibition pauses it, altering ramping dynamics and shifting anticipated motor (lick) timing.
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