The probability that frozen tissue will benefit the person who froze it is remote. The chance of developing acute lymphoblastic leukemia, the most common childhood cancer, currently stands at one in 20,000.
When Lorraine Kelly Donnelly felt a cramp in her left hand at the start of 2025, she didn't think anything of it. But when a week later the pain was still there, she made an appointment to see her GP.
When mitochondria are exposed to tissue or blood, they lose the electrical gradient across their outer membrane. Mitochondria that lack such a gradient are recognized by a cell's internal machinery as damaged and quickly destroyed. The vast majority of previous studies involved injecting 'naked' mitochondria directly into the bloodstream or tissue sites, but the approach isn't very efficient, so researchers often have to use 'ridiculous' doses of mitochondria.
Anyone living with schizophrenia understands the true limitations of current treatment options. Antipsychotics remain the single leading treatment for the disorder, and they are riddled with undesirable side effects. Weight gain, tardive dyskinesia, and excessive drowsiness are a few. Much research is devoted to expanding the range of medication options, and few academics have pursued other avenues. However, there is a possibility that treatment for schizophrenia can be approached through cellular methods if long-term research validates early signs of hope.
I am running. Ahead lie endless mangrove swamps, behind the green-blue waters of the Caribbean. My mind is rising away from my lurching body, which is on a treadmill and attached to a beeping machine by wires and tubes. Nurses circle. The gradient increases, as does the speed. Dignity slips away as my body fights for breath. They're after my "VO2 max", the amount of oxygen my body can absorb during my maximum capacity for exercise.
January 22, 2026 2 min read Add Us On GoogleAdd SciAm The National Institutes of Health's move to end support for research using fetal human tissue is clearly a political decision, not a scientific one, one expert says By Dan Vergano edited by Claire Cameron National Institutes of Health director Jay Bhattacharya speaks at the National Conservatism Conference in Washington, D.C., in 2025.
It arose out of safety concerns in 2022 in relation to the treatment of a number of patients with Spina Bifida who had spinal surgery at CHI at Temple Street. These concerns related to poor clinical outcomes of some complex spinal surgery, including a high incidence of post-operative complications and infections, and two particularly serious surgical incidents, which occurred in July and September 2022.
Before treatment began, participants underwent neuroimaging. Instead of relying on a single modality, the researchers fused structural connectivity (how regions are physically wired) with functional connectivity (how regions co-activate at rest). The goal was not to throw every possible feature at a black box, but to learn a constrained pattern-what the authors call structure-function "covariation"-that carries the most predictive signal for outcome. In other words, the model tries to find the smallest set of connections that meaningfully forecasts symptom change.
Summer passed Valerie Zeko by when she was 27, as she vegged out on the couch watching TV instead of seeing friends or exploring the overcast beach near her house. She later learned that period was her first episode of depression. I felt like the fog was in my head as well as outside, said Zeko, now 57, describing the mood disorder that would squelch her happiness, motivation and self-esteem for 28 years until she finally found effective treatment.
'Stem cell-based' treatments and just the latest aesthetic treatment marketed to those seeking to maintain or obtain youthful skin, but what exactly is involved and what's the evidence that they work It's hard to keep track of the number of scientifically based beauty treatments on offer these days. Most are aimed at middle-aged females with disposable incomes, who are willing to splash large amounts of money on their skin to counter the effects of time.
A study led by Stanford Medicine researchers has found that an injection blocking a protein linked to aging can reverse the natural loss of knee cartilage in older mice. The same treatment also stopped arthritis from developing after knee injuries that resemble ACL tears, which are common among athletes and recreational exercisers. Researchers note that an oral version of the treatment is already being tested in clinical trials aimed at treating age-related muscle weakness.
Mucopolysaccharidosis type II (MPS II), or Hunter syndrome, is a rare genetic disorder primarily affecting boys, caused by a deficiency in the enzyme needed to break down sugar molecules. This harmful buildup in cells and tissues impacts multiple body systems, causing frequent infections, organ enlargement and developmental disabilities. Management involves supportive care and enzyme replacement therapy, as there is currently no cure,
When a person suffers a stroke, physicians must restore blood flow to the brain as quickly as possible to save their life. But, ironically, that life-saving rush of blood can also trigger a second wave of damage - killing brain cells, fueling inflammation and increasing the odds of long-term disability. Now, in a study published in the journal Neurotherapeutics, Northwestern University scientists have developed an injectable regenerative nanomaterial that helps protect the brain during this vulnerable window.
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