#sex-differences-in-aging

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#x-chromosome-reactivation #hippocampus #plp1 #single-nucleus-rna-sequencing
Science
fromSilicon Canals
1 day ago

Women have a brain aging advantage men don't-the silent X chromosome - Silicon Canals

A previously 'silent' X chromosome in aging female mice reactivates over 20 hippocampal genes, including PLP1, boosting myelin-related expression and potentially protecting cognition.
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