When Lorraine Kelly Donnelly felt a cramp in her left hand at the start of 2025, she didn't think anything of it. But when a week later the pain was still there, she made an appointment to see her GP.
C4b-binding protein (C4BP) was identified as the missing cofactor that allows anti-phosphatidylethanolamine (aPE) antibodies to exert their damaging effects, linking them to thrombosis and pregnancy complications.
Our results are highly promising, especially since currently there are no approved treatments that address the underlying cause of Dravet syndrome. Since this gene regulation product targets the actual root cause of Dravet syndrome, we observed improvements in other developmental and cognitive symptoms, in addition to seizure control. This is unprecedented.
Anyone living with schizophrenia understands the true limitations of current treatment options. Antipsychotics remain the single leading treatment for the disorder, and they are riddled with undesirable side effects. Weight gain, tardive dyskinesia, and excessive drowsiness are a few. Much research is devoted to expanding the range of medication options, and few academics have pursued other avenues. However, there is a possibility that treatment for schizophrenia can be approached through cellular methods if long-term research validates early signs of hope.
A groundbreaking study found that adults who sit for 10 or more hours daily face a significantly higher risk of dementia compared to those who sit less. The research, which tracked over 50,000 adults using wearable devices, revealed that the risk increases dramatically after crossing that 10-hour threshold.
We knew that if you inject these nanoparticles into an animal model, the nanoparticles get taken up by antigen presenting cells and this resulted in increased regulatory T-cells and decreased inflammatory disease. However, we did not know how this happens,
If you get migraines, you already know they don't just stay in your head. The pounding pain might be the headline symptom, but the real story is how an attack can throw your entire body out of whack - making light feel blinding, everyday sounds unbearable, and even simple texts impossible to answer. That's because a migraine isn't just about sore neck muscles or scalp tension. It's a full-body neurological event, driven by a cascade of changes in the brain.
When a person suffers a stroke, physicians must restore blood flow to the brain as quickly as possible to save their life. But, ironically, that life-saving rush of blood can also trigger a second wave of damage - killing brain cells, fueling inflammation and increasing the odds of long-term disability. Now, in a study published in the journal Neurotherapeutics, Northwestern University scientists have developed an injectable regenerative nanomaterial that helps protect the brain during this vulnerable window.
Northwestern University has launched the Simpson Querrey Brain Health Institute (SQ-Brain), made possible by nearly $25 million in philanthropic funding from university trustee Kimberly K. Querrey ('22, '23 P). SQ-Brain envisions a future where our brains last as long as our bodies a world where brain health is continuously measurable, modifiable and monitorable across the lifespan, and where prevention of cognitive decline and brain injury is anchored in neurovascular biology and precision medicine.
