Medicine
fromFast Company
1 day agoThe $80,000 clue hiding in plain sight in U.S. healthcare
Genomic sequencing can identify genetic causes of neurological conditions but is often underutilized early in patient care.
Incyte tops this list due to its rare combination of commercial scale, cash generation, and pipeline depth. The company posted FY2025 revenue of $5.14 billion, up 21.2% YoY, anchored by Jakafi generating $828.2 million in Q4 2025 alone (+7% YoY) and Opzelura delivering $207.3 million (+28% YoY). With $3.58 billion in cash and 14 pivotal clinical trials underway, Incyte offers an acquirer immediate revenue, margin expansion potential, and a deep oncology pipeline spanning KRASG12D, CDK2 inhibition, and mutCALR.
Over two-thirds said they recommend their students consider careers outside academia. The majority had delayed hiring in their labs, and one-third had laid off workers. More than one in six said they have lost researchers to institutions in other countries since Trump took office. Sixty-eight percent said funding cuts and federal policy changes had moderately or significantly reduced the scope of their work.
Many other higher-income countries are grappling with rising obesity and diabetes, but the U.S. stands out for how consistently those risks translate into worse cardiovascular outcomes, and how wide the gaps are by income, race, ethnicity, and geography.
Massachusetts is known for being one of the least transparent states in the country when it comes to the accessibility of public records. The governor, judiciary, and state lawmakers enjoy broad exemptions for compliance with public records requests. There are no independent statewide audits of compliance with public records law.
"This result is very supportive of the value that foreign-born workers add to the health of our population. When you have an increase in immigration, you end up with more long-term care workers. It's additive, not substitutive."
The work, published in November, painted a disturbing yet complex picture that varies globally according to cancer type, sex, and national context. The study examined cases that occurred between 2000 and 2017 and found 13 cancers on the rise in those under 50 in at least 10 countries, and six cancers - colorectal, cervical, pancreatic, prostate, kidney and multiple myeloma - rising faster in younger adults than in older adults in at least five.
According to a recent WalletHub analysis, Massachusetts claimed the No. 1 spot among all 50 states thanks to its exceptional levels of higher education attainment and strong public school performance. The annual report, dubbed Most & Least Educated States in America (2026), used 18 metrics ranging from the share of residents with college degrees to public school performance and achievement disparities across gender and race.
For Massachusetts emergency physicians, that dream captures a simple truth: long ER waits rarely steam from care inside the department. Instead, doctors say they're the result of bottlenecks across a system stretched thin by staffing shortages, aging patients, limited hospital beds, and gaps in primary care.
Posted on TikTok nearly a week ago, the 10-second clip opens with a woman holding up a staff badge identifying her as a registered nurse in the emergency department at Mass General. She pulls out a canister of saline wound wash and sprays it at the camera while mouthing along to the A Day To Remember song "Miracle," which features the lyrics, "No weapon formed against me shall prosper / My will is stronger."
The 2025 America's Health Rankings report by the United Health Foundation ranked Massachusetts as the second healthiest state in the nation, falling shy of first-place New Hampshire. The state saw some progress with a 17% increase in cancer screenings among adults aged 40 to 75 between 2022 and 2024. It also had a low prevalence of obesity at only 27% of adults. Massachusetts last ranked No. 1 in 2017 and has remained in the top five since.
But these studies typically require large numbers of patients, huge amounts of data, and thorough follow-ups, none of which comes easy or free. The upshot is fewer investigations into scenarios that are clinically important but unlikely to yield a profit for the firms funding them. Accordingly, researchers have been developing an option that uses real-world data from insurers to save patients from falling through the cracks.
Whenever medical AI handles anything with medium to high risk, you want regulation: internal self-regulation or external governmental regulation. It's mostly been internal thus far, and there are differences in how each hospital system validates, reviews, and monitors healthcare AI. When done on a hospital-by-hospital basis like this, costs to do this kind of evaluation and monitoring can be significant, which means some hospitals can do this, and some can't.
If you find yourself in need of emergency care in Massachusetts, it could take a while. The Bay State ranks No. 3 in the U.S. for longest average time patients spend in the emergency department, according to World Population Review. Patients here spend an average of 189 minutes - more than three hours - in the ER before leaving the hospital. Only Maryland (228 minutes) and Delaware (195 minutes) report longer average delays.
In 2026, the US healthcare system is changing. Enhanced Affordable Care Act subsidies have expired, causing premiums for marketplace plans to spike - and pricing some families out of health insurance entirely. President Donald Trump's One Big Beautiful Bill Act will reduce coverage for some patients with Medicaid and funding for hospitals, especially those in rural areas. Costs for Medicare and private insurance are also rising: Employer-based healthcare premiums have increased by 9%, the largest rise in more than a decade.