#infectious-disease-epidemiology

#infectious-disease-epidemiology

Antibiotics are essential for modern medicine, but bacteria are evolving and developing resistance, turning routine infections into life-threatening conditions. A global analysis estimates that antibiotic-resistant infections could cause over 39 million deaths by 2050.

GOARN, which includes more than 310 national public health agencies, United Nations agencies, academic institutions, and nongovernmental groups, helps identify and manage infectious disease outbreaks worldwide. Since it was established in 2000, GOARN says it has helped manage more than 175 global health emergencies across 114 countries.

I am open-minded; I believe in integrative practices, and I agree that the medical establishment can be arrogant and unduly influenced by the pharmaceutical industry, which now funds so much of medical research. But I fully understand Scherer's frustration with his interminable discussions with Kennedy about scientific articles.

The U.S. is no longer part of the World Health Organization. After the Trump administration declared its intention to pull the country out of the global public health agency one year ago, on Thursday it formally followed through, ending its commitment to the organization after 78 years. Withdrawing the U.S. from the WHO was one of Trump's day one priorities. Now, after the required one year notice period, the deed is done.

Risks of outbreaks with pandemic potential rise with increasing land-use change, biodiversity loss and climate change. The Pandemic Agreement adopted by the World Health Assembly in 2025 marks a historic shift that establishes the One Health approach as a legally binding obligation for pandemic prevention.

Bats carry a lot of very deadly pathogens like Ebola virus, Nipah, Hendra, coronavirus, and also rabies virus. People are finding more and more bat-borne viruses. When such viruses are transmitted to humans, the results are often fatal so there's a lot of interest in trying to prevent spillover in the first place.

In a study published in Science Advances, researchers in China fed Aedes aegypti mosquitoes blood that contained either a vaccine against Nipah virus or the rabies virus. The viruses, contained in the vaccines, replicated inside the insects and reached their salivary glands, allowing them to pass on the vaccine when feeding on bats or when the bats ate the insects.

DNA variants near a gene called MSRB3 - which is important for hearing in humans - could determine whether a dog's ears are pendulous like a basset hound's or stubby like a rottweiler's. Researchers analysed the genomes of thousands of canines and found that small, single-letter changes to DNA in a region of the genome near MSRB3 could boost the gene's activity. The boost can increase the rate at which ear cells proliferate, resulting in longer ears.

Each day, they pore over reams of data about how the virus is evolving worldwide, how well last year's shot performed, and which strains might be easiest to mass produce for a vaccine. The meeting, convened by the World Health Organization twice a year, is a critical moment for the WHO's Global Influenza Surveillance and Response System.

For the first time, cameras in Africa captured a 'dynamic network' of wildlife interacting with thousands of infected bats believed to be carrying the Marburg virus, which is a rare but extremely dangerous disease that belongs to the same family as Ebola. The new videos revealed at least 14 different types of animals, including leopards, hyenas, monkeys, birds and rats, actively hunting herds of Egyptian fruit bats.

Perhaps the most significant milestone was the adoption by WHO Member States of the Pandemic Agreement, a landmark step towards making the world safer from future pandemics. Alongside this, amendments to the International Health Regulations came into force, including a new pandemic emergency alert level designed to trigger stronger global cooperation. And to sustainably finance the WHO's work, governments in a historic show of support increased their contributions to our core budget.

We see the percentage of outpatients' visits for influenza-like illnesses (proven influenza cases and not tested but similar cases) in 2025 and the beginning of 2026, compared to the last few years. The current outbreak is represented by a dark red line that is higher than in previous years and is expected to continue rising with the start of school this week.

"What we've identified here could help improve adherence to vaccination quicker if we target the right people," he says.

One type of flu virus, called A H3N2, historically has caused the most hospitalizations and deaths in older people. So far this season, that's the type most frequently reported. Even more concerning, more than 91% of the H3N2 infections analyzed were a new version known as the subclade K variant that differs from the strain in this year's flu shots.