#immunology

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Notching up a win: fresh tools for activating Notch

New tools for activating Notch signalling could transform T-cell therapy development, potentially reversing previous limitations in laboratory mimicry.

A spatial human thymus cell atlas mapped to a continuous tissue axis - Nature

The thymus is essential for T cell maturation, impacting immune system development and self-tolerance.

A cell atlas foundation model for scalable search of similar human cells

SCimilarity framework enhances the analysis of single-cell RNA-seq data by enabling efficient cell profile queries and discovery of cell-disease relationships.

Engineered receptors for soluble cellular communication and disease sensing

The SNIPR architecture enhances therapeutic targeting in synthetic biology through low baseline activity and specific activation by soluble ligands.
#medical-research

Grant for $120M will fund anchor tenant at UCLA Research Park

Dr. Gary Michelson has pledged $120 million to establish a medical institute at UCLA focused on immunology and disease prevention.

Accelerating Discoveries in Immunobiology Through Collaboration - News Center

The Center for Human Immunobiology rapidly fosters collaboration to advance immunology research and develop treatments for immune-related diseases.

Gasdermin D-mediated metabolic crosstalk promotes tissue repair - Nature

Interdisciplinary collaboration in medical research enhances innovation and problem-solving capabilities.

Grant for $120M will fund anchor tenant at UCLA Research Park

Dr. Gary Michelson has pledged $120 million to establish a medical institute at UCLA focused on immunology and disease prevention.

Accelerating Discoveries in Immunobiology Through Collaboration - News Center

The Center for Human Immunobiology rapidly fosters collaboration to advance immunology research and develop treatments for immune-related diseases.

Gasdermin D-mediated metabolic crosstalk promotes tissue repair - Nature

Interdisciplinary collaboration in medical research enhances innovation and problem-solving capabilities.
moremedical-research

New link between shift work and obesity outlined by researchers at Trinity College Dublin

Interleukin-17A plays a key role in fat storage regulation, offering new therapeutic potential for obesity and metabolic disorders.
#research

Your diet can change your immune system - here's how

Innovative research approaches are enhancing our understanding of nutrition's impact on immunity, bridging gaps in scientific evidence.

These scientists are trying to build a fungal-resistant future

Fungal infections pose a significant global health threat, especially to immunocompromised individuals, highlighting the need for improved prevention and treatment strategies.

Your diet can change your immune system - here's how

Innovative research approaches are enhancing our understanding of nutrition's impact on immunity, bridging gaps in scientific evidence.

These scientists are trying to build a fungal-resistant future

Fungal infections pose a significant global health threat, especially to immunocompromised individuals, highlighting the need for improved prevention and treatment strategies.
moreresearch
#public-health

Now Is the Perfect Time to Test Your 'Cold' for COVID

COVID-19 cases are rising sharply, necessitating timely testing and vaccinations, especially as the flu and RSV seasons approach.

Covid on the rise as experts say England has capitulated' to the virus

Covid cases are rising in England, prompting concerns about societal complacency and the need for more preventive measures.

Fears of fast spread of XEC Covid strain after many haven't had vaccines in long time

The new Covid XEC variant may spread quickly due to low vaccination levels, but is not expected to lead to new restrictions.

Paul: When medical research gets things wrong, doctors dig in

The misguidance on peanut avoidance contributed to the rise in childhood peanut allergies in America, contrary to principles of immunology.

New COVID-19 XEC variant circulating just before fall

The new COVID-19 variant XEC is not anticipated to dominate this winter, with symptoms similar to previous strains.

Faculty awards, honors, and activities

The article highlights the significant contributions and achievements of various members of the Harvard Chan School community in the fields of public health, AI research, global health, immunology, and nutrition.

Now Is the Perfect Time to Test Your 'Cold' for COVID

COVID-19 cases are rising sharply, necessitating timely testing and vaccinations, especially as the flu and RSV seasons approach.

Covid on the rise as experts say England has capitulated' to the virus

Covid cases are rising in England, prompting concerns about societal complacency and the need for more preventive measures.

Fears of fast spread of XEC Covid strain after many haven't had vaccines in long time

The new Covid XEC variant may spread quickly due to low vaccination levels, but is not expected to lead to new restrictions.

Paul: When medical research gets things wrong, doctors dig in

The misguidance on peanut avoidance contributed to the rise in childhood peanut allergies in America, contrary to principles of immunology.

New COVID-19 XEC variant circulating just before fall

The new COVID-19 variant XEC is not anticipated to dominate this winter, with symptoms similar to previous strains.

Faculty awards, honors, and activities

The article highlights the significant contributions and achievements of various members of the Harvard Chan School community in the fields of public health, AI research, global health, immunology, and nutrition.
morepublic-health
#therapeutic-strategies

Structure of a fully assembled T-cell antigen receptor - Nature

Interdisciplinary collaboration enhances research in infection and immunity.

Yo-yo dieting accelerates cardiovascular disease by reprogramming the immune system

Understanding immune modulation can lead to novel therapies for chronic diseases.
Advancing research in immunology is essential for improving disease management through targeted therapies.

Structure of a fully assembled T-cell antigen receptor - Nature

Interdisciplinary collaboration enhances research in infection and immunity.

Yo-yo dieting accelerates cardiovascular disease by reprogramming the immune system

Understanding immune modulation can lead to novel therapies for chronic diseases.
Advancing research in immunology is essential for improving disease management through targeted therapies.
moretherapeutic-strategies

The microbiome is worlds within worlds

The human microbiome influences health and mortality through complex interactions among microorganisms.

The Truth About Man Flu'

Man flu reflects a humorous stereotype revealing real differences in how men and women react to illness, backed by immunological and behavioral studies.

Immune system adaptation during gender-affirming testosterone treatment - Nature

GAHT significantly influences immune response in transgender individuals, indicating broader effects of gonadal steroids on human immunity.
#collaboration

Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis - Nature

Collaboration across institutions fosters innovation in cardiovascular and immunology research, yielding better health outcomes.

The mRNA miracle workers

The collaboration between Drew Weissman and Katalin Karikó led to the development of the Pfizer and Moderna COVID vaccines in 2020.
The mRNA COVID vaccine directs cells to create spike proteins, building defenses against the virus, ultimately helping fight against it.

Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis - Nature

Collaboration across institutions fosters innovation in cardiovascular and immunology research, yielding better health outcomes.

The mRNA miracle workers

The collaboration between Drew Weissman and Katalin Karikó led to the development of the Pfizer and Moderna COVID vaccines in 2020.
The mRNA COVID vaccine directs cells to create spike proteins, building defenses against the virus, ultimately helping fight against it.
morecollaboration

Major gift accelerates transformation of old mall into UCLA research hub

Billionaire donation boosts UCLA's research center focused on immunology and disease prevention.

Understanding Epigenetic Control of Antibody Responses - News Center

BAF complexes regulate antibody responses; mutations in these complexes contribute to immune dysfunction linked to cancer.

Biotech Financing Roundup: Jade Bio's Launch, Brenig's Debut, Confo's Cash & More - MedCity News

Developing drugs for autoimmune diseases faces challenges with immune response. New biotech companies are advancing novel therapies in immunology and inflammation.

Study Uncovers Novel Mechanisms Behind Food Allergies - News Center

Precise role of DOCK8 in IgA production in gut
Imbalance in gut's mucosal tissue can lead to food allergies

German man got 217 COVID shots over 29 months-here's how it went

Excessive vaccinations did not weaken immune response
Chronic exposure to vaccinations may lead to immune tolerance
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