#gut-brain-axis

#gut-brain-axis

This could open up some interesting possibilities for therapeutic interventions for depression-like behaviors or maladaptive changes in motivational behaviors down the road where microglia are known to play a really important role.

They created an artificial 'mental map', with pleasantness along one axis and bodily reactions along the other, and charted how the brain responded while watching clips from films. The results revealed clear groupings in the way that our brains represent emotion - with guilt, anger and disgust in one corner and happiness, satisfaction and pride in the other.

Young, two-month-old lab mice housed with older, 18-month-old mice showed really impaired cognition. Researchers exposed young mice raised in a sterile, microbe-free environment to gut bacteria from old mice, causing the younger animals to perform worse on cognitive tests, as if they had prematurely aged, just like the cohoused mice.

The article from the journal argues that the gut-autism axis is a house of cards built on lousy studies with inconsistent data. They assert that the studies are contradictory and that too much emphasis is placed on dubious mouse models. It is notoriously challenging to nail down microbial causes of disease—it is hard enough to simply identify a normal microbiome.

There are some communities that are very unhealthy where the diversity is higher. Low diversity is not a universal marker. We found something that at first seemed surprising. That a healthy microbiome has lots of competition. These bugs are all going after the same food. In an unhealthy gut, on the other hand, you see tight cooperation - microorganisms are helping each other out.

Rumination activates the default mode network (DMN) - the brain's self-referential processing system. This is the neural circuitry that fires when you're thinking about yourself in relation to others: your identity, your social standing, your mistakes. It's the brain asking, over and over, What does this say about me?

Adult content has never been as accessible as it is now, thanks to the internet. Hell, online smut played a major role in the rise of the web itself in the 1990s. With that glut of porn, some have voiced concerns that some people are consuming too much of the stuff or even becoming addicted, which they claim could have consequences like regulating emotions or impaired sexual functioning.

Everything on my Instagram feed at the moment is about worms and parasites, she told the Wall Street Journal, ominously adding: I don't know what the heck is going to come out. Maybe your social media feeds aren't full of posts about worms and parasites, in which case, congratulations. But type parasite cleanse into TikTok or Instagram and you'll be inundated with so-called experts peddling expensive herbal supplements that promise to detox the body and rid it of harmful worms and parasites.

Gut bacteria are crucial to ensuring healthy digestion and defecation. But two species of bacteria may also be the cause of constipation: according to a new study, Bacteroides thetaiotaomicron and Akkermansia muciniphila appear to work in concert to break down colonic mucin, the slimy coating in our colons that keeps our poo moving along. Too little mucin means a drier and more constipation-prone colon.

Anyone living with schizophrenia understands the true limitations of current treatment options. Antipsychotics remain the single leading treatment for the disorder, and they are riddled with undesirable side effects. Weight gain, tardive dyskinesia, and excessive drowsiness are a few. Much research is devoted to expanding the range of medication options, and few academics have pursued other avenues. However, there is a possibility that treatment for schizophrenia can be approached through cellular methods if long-term research validates early signs of hope.

More than 7 million Americans are living with Alzheimer's disease, the most common cause of dementia. And that number could double by 2050 if more people don't take steps to protect their brain health. While no single food can prevent cognitive decline, research shows that diet plays a powerful role in how the brain ages. The MIND diet is one science-backed way to make a positive impact.

Our brain interprets grief as stress. As a result, it activates our stress-response systems, especially the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic nervous system. These systems release stress hormones such as cortisol and adrenaline, which are meant to protect the body in short-term crises. In acute grief, these responses are adaptive. They help us cope with shock and disruption. If unresolved, however, the same systems can become dysregulated.