#genomic-surveillance

#genomic-surveillance

Kelly Chibale describes the drug discovery process as a fairy-tale quest, stating, 'It doesn't mean that there aren't surprises or miracles. They do happen, but you have to kiss many frogs before you meet the prince.' This metaphor illustrates the challenges and unpredictability in finding effective medicines.

Bacterial meningitis has become rare in the UK, but small clusters occasionally occur. The outbreak has affected 29 people, killing two, and is labeled 'unprecedented'.

I am open-minded; I believe in integrative practices, and I agree that the medical establishment can be arrogant and unduly influenced by the pharmaceutical industry, which now funds so much of medical research. But I fully understand Scherer's frustration with his interminable discussions with Kennedy about scientific articles.

Risks of outbreaks with pandemic potential rise with increasing land-use change, biodiversity loss and climate change. The Pandemic Agreement adopted by the World Health Assembly in 2025 marks a historic shift that establishes the One Health approach as a legally binding obligation for pandemic prevention.

Martschenko's argument is largely that genetic research and data have almost always been used thus far as a justification to further entrench extant social inequalities. But we know the solutions to many of the injustices in our world-trying to lift people out of poverty, for example-and we certainly don't need more genetic research to implement them. Trejo's point is largely that more information is generally better than less.

The U.S. is no longer part of the World Health Organization. After the Trump administration declared its intention to pull the country out of the global public health agency one year ago, on Thursday it formally followed through, ending its commitment to the organization after 78 years. Withdrawing the U.S. from the WHO was one of Trump's day one priorities. Now, after the required one year notice period, the deed is done.

Bats carry a lot of very deadly pathogens like Ebola virus, Nipah, Hendra, coronavirus, and also rabies virus. People are finding more and more bat-borne viruses. When such viruses are transmitted to humans, the results are often fatal so there's a lot of interest in trying to prevent spillover in the first place.

At the end of January, Washington, DC, saw an extremely unusual event. The MAHA Institute, which was set up to advocate for some of the most profoundly unscientific ideas of our time, hosted leaders of the best-funded scientific organization on the planet, the National Institutes of Health. Instead of a hostile reception, however, Jay Bhattacharya, the head of the NIH, was greeted as a hero by the audience, receiving a partial standing ovation when he rose to speak.

We now have our first confirmed measles case of 2026 in the Bay Area and the first of 2026 in California as an unvaccinated international traveler apparently brought some back home to San Mateo County. Though first of 2026 may not be that distinct of a deal, considering we saw another new measles case in Contra Costa County when there was still two more days in 2025. [KQED]

Each day, they pore over reams of data about how the virus is evolving worldwide, how well last year's shot performed, and which strains might be easiest to mass produce for a vaccine. The meeting, convened by the World Health Organization twice a year, is a critical moment for the WHO's Global Influenza Surveillance and Response System.

Laboratories turned to a smart workaround when COVID‑19 testing kits became scarce in 2020. They mixed samples from several patients and ran a single test. If the test came back negative, everyone in it was cleared at once. If it was positive, follow-up tests would zero in on who was infected. That strategy, known as group testing, saved valuable time, money, and resources.

DNA variants near a gene called MSRB3 - which is important for hearing in humans - could determine whether a dog's ears are pendulous like a basset hound's or stubby like a rottweiler's. Researchers analysed the genomes of thousands of canines and found that small, single-letter changes to DNA in a region of the genome near MSRB3 could boost the gene's activity. The boost can increase the rate at which ear cells proliferate, resulting in longer ears.

We see the percentage of outpatients' visits for influenza-like illnesses (proven influenza cases and not tested but similar cases) in 2025 and the beginning of 2026, compared to the last few years. The current outbreak is represented by a dark red line that is higher than in previous years and is expected to continue rising with the start of school this week.

Perhaps the most significant milestone was the adoption by WHO Member States of the Pandemic Agreement, a landmark step towards making the world safer from future pandemics. Alongside this, amendments to the International Health Regulations came into force, including a new pandemic emergency alert level designed to trigger stronger global cooperation. And to sustainably finance the WHO's work, governments in a historic show of support increased their contributions to our core budget.

One type of flu virus, called A H3N2, historically has caused the most hospitalizations and deaths in older people. So far this season, that's the type most frequently reported. Even more concerning, more than 91% of the H3N2 infections analyzed were a new version known as the subclade K variant that differs from the strain in this year's flu shots.

It's clear that the worst is far from over for the NHS this winter, with hospitals again experiencing a rise in patients admitted with flu and other respiratory virus cases last week.

Public health consultant Dr Ross Keat said supporting people earlier to make small preventative changes would make "a big difference later on". Some 3,500 people in the north of the island within that age bracket are eligible for the checks. The checks will be carried out by two pre-existing nurses that support GP staff and would not replace GP appointments, Keat explained, adding that the cost would be minimal and absorbed by Ramsey Group Practice.

If you're based in the United States, you've probably gotten used to government bodies issuing nationwide alerts - including ones that relate to public health. These have, historically, been good ways for health-conscious people to know what to look out for and for regional public health experts to develop strategies to help keep potential outbreaks contained.Unfortunately, now both individuals and institutions are reckoning with a big question: what to do when those warnings are much smaller in number?

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