#genetic-health-risks

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fromIndependent
9 hours ago

'It will be life-changing': Screening for two devastating genetic disorders in newborns to begin today

The heel prick test will now be accompanied by testing for spinal muscular atrophy (SMA), a rare muscle-wasting condition that can potentially lead to a child's death by the age of two.
Medicine
#ai-in-healthcare
fromWIRED
3 days ago
Health

Meta's New AI Asked for My Raw Health Data-and Gave Me Terrible Advice

Health
fromWIRED
3 days ago

Meta's New AI Asked for My Raw Health Data-and Gave Me Terrible Advice

Medical experts express concerns about uploading personal health data to AI models due to privacy and control issues.
Medicine
fromwww.bbc.com
3 days ago

ChatGPT 'uncovered woman's rare condition' after years of misdiagnosis

AI helped diagnose a rare condition after years of misdiagnosis, leading to genetic confirmation of hereditary spastic paraplegia.
Cancer
fromNews Center
4 days ago

Long Non-Coding RNA May be a Promising Therapeutic Target for Cancer - News Center

A long non-coding RNA, IGF1R-AS1, activates oncogenic pathways in prostate cancer, highlighting its potential as a therapeutic target.
#aging
OMG science
fromNature
6 days ago

This method to reverse cellular ageing is about to be tested in humans

Yuancheng Ryan Lu's research on reprogramming retinal nerve cells could lead to restoring eyesight and rejuvenating organs.
Health
fromenglish.elpais.com
3 weeks ago

100 experts were unable to agree on whether aging is an illness, or when it begins

Aging lacks a universally accepted definition, with significant disagreement among experts on its causes and implications.
OMG science
fromNature
6 days ago

This method to reverse cellular ageing is about to be tested in humans

Yuancheng Ryan Lu's research on reprogramming retinal nerve cells could lead to restoring eyesight and rejuvenating organs.
Health
fromenglish.elpais.com
3 weeks ago

100 experts were unable to agree on whether aging is an illness, or when it begins

Aging lacks a universally accepted definition, with significant disagreement among experts on its causes and implications.
#gene-editing
Medicine
fromArs Technica
3 days ago

Clinical trial shows gene editing works for -Thalassaemia, too

An improved gene editing system reactivates a fetal hemoglobin gene to treat β-Thalassaemia, building on CRISPR's success with sickle-cell anemia.
Medicine
fromArs Technica
3 days ago

Clinical trial shows gene editing works for -Thalassaemia, too

An improved gene editing system reactivates a fetal hemoglobin gene to treat β-Thalassaemia, building on CRISPR's success with sickle-cell anemia.
#genomics
fromNature
1 week ago
Science

The 1000 Chinese Pangenome empowers medical and population genetics - Nature

fromTechCrunch
1 week ago
Data science

Mantis Biotech is making 'digital twins' of humans to help solve medicine's data availability problem | TechCrunch

fromwww.cbc.ca
2 months ago
Public health

New project aims to map genomes of Black Canadians, provide better health outcomes | CBC News

fromNature
1 week ago
Science

The 1000 Chinese Pangenome empowers medical and population genetics - Nature

Data science
fromTechCrunch
1 week ago

Mantis Biotech is making 'digital twins' of humans to help solve medicine's data availability problem | TechCrunch

Large language models can enhance genomics and clinical practices, but struggle with rare diseases due to data scarcity.
fromwww.cbc.ca
2 months ago
Public health

New project aims to map genomes of Black Canadians, provide better health outcomes | CBC News

#genetics
Health
fromThe Washington Post
1 week ago

One way to live longer: Win the genetic lottery

Genetic factors account for about 50% of human lifespan, significantly higher than the previously estimated 20%.
Medicine
fromNature
5 days ago

Why obesity drugs work better for some people: these genes hold clues

Genetic variants influence individual responses to obesity drugs, affecting weight loss and side effects.
Medicine
fromwww.theguardian.com
4 days ago

Genetics may help explain why results from weight-loss jabs vary, say scientists

Genetic variations in gut hormone pathways may explain differing responses to weight-loss medications like GLP1 receptor agonists.
Medicine
fromNews Center
1 week ago

Uncovering a Genetic Driver of Rare Early-Onset Dementia - News Center

A new genetic risk factor for early-onset frontotemporal dementia has been identified, significantly increasing the odds of developing the disease.
Cancer
fromNature
6 days ago

New drugs take aim at one of cancer's deadliest mutations

Researchers are developing innovative strategies to target the cancer-causing KRAS protein, previously deemed 'undruggable', showing promising results in clinical trials.
#cloning
Science
fromFuturism
1 week ago

A Startup Has Been Quietly Pitching Cloned Human Bodies to Transfer Your Brain Into

Cloning efforts have evolved from animals to controversial human embryo models, with ambitions for brainless human clones for organ transplants.
OMG science
fromNature
2 weeks ago

Can a mouse be cloned indefinitely? Decades-long experiment has answers

Asexual reproduction in mice is unsustainable due to accumulating mutations, limiting the potential for successful cloning.
Science
fromFuturism
1 week ago

A Startup Has Been Quietly Pitching Cloned Human Bodies to Transfer Your Brain Into

Cloning efforts have evolved from animals to controversial human embryo models, with ambitions for brainless human clones for organ transplants.
OMG science
fromNature
2 weeks ago

Can a mouse be cloned indefinitely? Decades-long experiment has answers

Asexual reproduction in mice is unsustainable due to accumulating mutations, limiting the potential for successful cloning.
Medicine
fromNature
5 days ago

Saturation editing of RNU4-2 reveals distinct dominant and recessive disorders - Nature

De novo variants in RNU4-2 cause ReNU syndrome, a neurodevelopmental disorder characterized by developmental delays and other severe symptoms.
Medicine
fromThe New Yorker
4 days ago

Are Unapproved Peptides Worth the Risk?

Peptides are short chains of amino acids that may enhance strength and recovery, but their safety and efficacy in humans are largely unknown.
Artificial intelligence
fromwww.npr.org
1 month ago

ChatGPT might give you bad medical advice, studies warn

AI chatbots provide medical information to millions daily but often mislead users because people lack training in effectively communicating symptoms to these systems.
Science
fromNature
3 weeks ago

Synthetic circuits for cell ratio control - Nature

Synthetic biology enables artificial cell differentiation and division of labor by engineering genetic and epigenetic circuits that mimic natural stem cell asymmetric division processes.
fromFast Company
1 week ago

AI is coming for superbugs

Antibiotics are essential for modern medicine, but bacteria are evolving and developing resistance, turning routine infections into life-threatening conditions. A global analysis estimates that antibiotic-resistant infections could cause over 39 million deaths by 2050.
Medicine
Health
fromInsideHook
4 weeks ago

Medical Experts Recommend a Genetic Test for Heart Disease Risk

The American Heart Association and American College of Cardiology now recommend genetic testing for lipoprotein(a) to identify heart disease risk factors unaffected by diet and lifestyle changes.
fromNature
1 week ago

DNA damage burden causes selective CUX2 neuron loss in neuroinflammation - Nature

DNA damage can originate from internal sources like metabolic by-products or normal cellular activities, as well as external factors such as cosmic radiation, diet, and pollution.
Medicine
Mental health
fromPsychology Today
1 month ago

A Genetic Map Redrawing the Borders of Mental Illness

Five broad genetic families underlie 14 psychiatric disorders, suggesting diagnostic categories reflect shared biological landscapes rather than distinct diseases.
Science
fromNature
1 month ago

From cancer to Alzheimer's: could a renewed focus on energy transform biomedicine?

Energy flow, governed by universal physics principles, provides a more fundamental understanding of biological processes and disease than molecular mechanisms alone.
Left-wing politics
fromTruthout
1 month ago

Reproductive Tech That Promises Smart Babies Is Peddling Soft Eugenics

Reproductive tech companies now offer embryo genetic screening for intelligence and disease, raising concerns about eugenics, disability discrimination, and wealth-based genetic enhancement.
fromwww.theguardian.com
1 month ago

I clicked on a button and everything changed': how a DNA test turned my life upside-down

It was another detail that the rest of the family apparently knew but had never told me; they thought I already knew. The biology mattered less to me than the secret. Dad had been adopted, it turned out. A classic affliction of the 1950s, in which young, unmarried couples were forced to give away their newborn babies.
Books
Cancer
fromenglish.elpais.com
1 month ago

Three sisters and a dilemma: what to do when you inherit a genetic mutation that can cause cancer

Three sisters discovered they carry the BRCA1 gene mutation, which significantly increases breast and ovarian cancer risk, after their cousin's rapid cancer diagnosis prompted family genetic testing.
#genetic-screening
fromNature
2 months ago
Public health

Nationwide genetic screening proves effective at catching disease risk early

fromNature
2 months ago
Public health

Nationwide genetic screening proves effective at catching disease risk early

Medicine
fromwww.bbc.com
3 weeks ago

Scotland becomes first in UK to test newborns for rare genetic condition

Scotland is the first UK region to test newborns for Spinal Muscular Atrophy, enabling early treatment to improve life expectancy.
Science
fromNature
1 month ago

Daily briefing: How DNA testing can tell identical twins apart

Advanced forensic techniques including whole-genome sequencing and epigenetic analysis can differentiate between identical twins in criminal investigations, while GLP-1 drugs show potential in reducing addiction across multiple substances, and researchers have successfully synthesized hexagonal diamond.
Healthcare
fromwww.theguardian.com
1 month ago

Unbelievably dangerous': experts sound alarm after ChatGPT Health fails to recognise medical emergencies

ChatGPT Health fails to recognize medical emergencies in over half of cases, potentially endangering users by recommending home care instead of emergency department visits.
Cancer
fromNature
1 month ago

Cancer blood tests are everywhere. Do they really work?

Multi-cancer early detection blood tests show promise but lack regulatory approval and rigorous trial evidence, with initial results indicating limited effectiveness in improving cancer outcomes.
Public health
fromwww.independent.co.uk
2 months ago

Genetic tests for cancer on NHS to help families detect Jolie' gene

The NHS will build a 120-gene database to improve cancer prevention, enabling earlier screening and personalised treatments for patients and at-risk family members.
Information security
fromTechRepublic
2 months ago

23andMe Data Breach Settlement Deadline Is Near: Here's How Much You Could Get - TechRepublic

Eligible 23andMe customers affected by the Oct 2023 breach must file claims by Feb 17, 2026 to receive cash payments or five years of monitoring services.
fromwww.nature.com
1 month ago

Genetically encoded assembly recorder temporally resolves cellular history

GEMINI leverages a computationally designed protein assembly as an intracellular memory device to record the history of individual cells. GEMINI grows predictably within live cells, capturing cellular events as tree-ring-like fluorescent patterns for imaging-based retrospective readout. Absolute chronological information of activity histories is attainable with hour-level accuracy.
Mental health
fromPsychology Today
2 months ago

Global Study Identifies Genetic Links to Depression

Genetic analyses have identified hundreds of variants linked to depression and revealed existing non-psychiatric drugs as potential treatment candidates.
#y-chromosome-loss
OMG science
fromHarvard Gazette
2 months ago

Why did that cancer cell become drug-resistant? - Harvard Gazette

TimeVault records and stores cellular gene-expression history inside living cells, enabling retrieval of past gene-activity information to study differentiation, stress responses, adaptation, and drug resistance.
Mental health
fromPsychology Today
2 months ago

Very Different Psychiatric Diagnoses Share Common Genes

Alcohol, cannabis, opioid, and nicotine use disorders share substantial genetic liability and cluster together as a single brain disorder, supporting a unified addiction-liability.
fromArs Technica
1 month ago

Have we leapt into commercial genetic testing without understanding it?

Martschenko's argument is largely that genetic research and data have almost always been used thus far as a justification to further entrench extant social inequalities. But we know the solutions to many of the injustices in our world-trying to lift people out of poverty, for example-and we certainly don't need more genetic research to implement them. Trejo's point is largely that more information is generally better than less.
Science
Mental health
fromPsychology Today
1 month ago

The Effect of Family History on Brain Injury

Knowing one’s family history and cultural roots is essential to reclaim identity, process grief, and repair relationships after catastrophic brain injury.
Cancer
fromenglish.elpais.com
1 month ago

Douglas Hanahan, biologist: We don't necessarily need a cure, what we really need is cancer without disease'

Cancer cells acquire hallmarks: uncontrolled proliferation, evasion of growth barriers, resistance to programmed death, and relative immortality, driving tumor diversity and treatment variability.
Public health
fromNature
2 months ago

More than one-third of cancer cases are preventable, massive study finds

Nearly 40% of global new cancer cases in 2022 were attributable to modifiable risk factors, primarily tobacco smoking, infections, and alcohol consumption.
Science
fromwww.scientificamerican.com
2 months ago

How long you live may depend much more on your genes than scientists thought

Heritability of human lifespan roughly doubles to about 50% when extrinsic mortality is removed, showing a stronger genetic influence on intrinsic aging.
Medicine
fromThe Atlantic
1 month ago

Their Mutated Genes Were Supposed to Be Harmless

People who carry single-gene mutations for disorders like thalassemia can experience real health effects, including lethargy and fainting, despite being labeled asymptomatic.
Public health
fromMail Online
2 months ago

Scientists discover 38% of cancers are caused by 30 lifestyle habits

Thirty-eight percent of global cancers in 2022 were attributable to 30 modifiable risk factors, so over one in three cases could be prevented.
fromNature
1 month ago

AI tools can design genomes. Will they upend how life evolves?

Biology is undergoing a transformation. After centuries of studying life as it evolves naturally, researchers are now using a combination of computation and genome engineering to intervene, generating new proteins and even whole bacteria from scratch. The use of artificial-intelligence tools to design biological components, an approach known as generative biology, is set to turbocharge this area of research. Just last year, scientists used AI-assisted design to produce artificial genes that can be expressed in mammalian cells.
Science
fromwww.theguardian.com
1 month ago

What is colorectal cancer and is it preventable?

Actor James Van Der Beek died on 11 February, aged 48; he had been diagnosed in 2023 with colorectal cancer. According to the World Health Organization, colorectal cancer is the third most common cancer and the second leading cause of cancer-related deaths worldwide. While rates are declining overall, cases among younger people are rising. This is a curable cancer if diagnosed early, says Dr Deirdre Cohen, director of the gastrointestinal oncology program for the Mount Sinai health system and an associate professor of medicine. It's important to bring any symptoms to the attention of your physician.
Public health
fromWIRED
2 months ago

HHS Is Making an AI Tool to Create Hypotheses About Vaccine Injury Claims

Kennedy has also called for overhauling the current safety monitoring system for vaccine injury data collection, known as Vaccine Adverse Event Reporting System, or VAERS, claiming that it suppresses information about the true rate of vaccine side effects. He has also proposed changes to the federal Vaccine Injury Compensation Program that could make it easier for people to sue for adverse events that haven't been proven to be associated with vaccines.
Public health
Science
fromWIRED
2 months ago

He Went to Prison for Gene-Editing Babies. Now He's Planning to Do It Again

He Jiankui created the first gene-edited babies, was jailed and banned, and now seeks to resume controversial genetic research despite widespread germline-editing prohibitions.
Medicine
fromNature
1 month ago

World-first stem-cell therapy shows promise for treating spina bifida in the womb

Placenta-derived stem cells applied to exposed fetal spinal cords during in utero surgery show safety and reverse hindbrain herniation in myelomeningocele cases.
Medicine
fromenglish.elpais.com
1 month ago

The very long road from a cancer cure' in mice to one in humans

Promising mouse cancer cures often fail to become safe, effective human drugs; premature media claims can create false patient expectations and hinder responsible research progress.
Science
fromwww.scientificamerican.com
2 months ago

Google DeepMind unleashes new AI to investigate DNA's dark matter'

AlphaGenome predicts functional effects of mutations in long noncoding DNA sequences up to one million base pairs, helping interpret genomic variants for disease research.
Medicine
fromNature
2 months ago

How DeepMind's genome AI could help solve rare disease mysteries

AlphaGenome uses AI to predict effects of non-coding DNA mutations, helping interpret previously triaged variants and aiding diagnosis of undiagnosed rare diseases.
Science
fromNature
2 months ago

Construction of complex and diverse DNA sequences using DNA three-way junctions - Nature

DNA writing remains limited by short oligo synthesis and two-way junction assembly methods, hindering affordable, scalable construction of large, complex synthetic DNA.
Science
fromAxios
1 month ago

The narrow slice of data that worries biosecurity experts

Certain biological datasets that materially increase misuse risk should be governed like sensitive health records while most biological data remains openly accessible.
Science
fromwww.nature.com
2 months ago

Scalable and multiplexed recorders of gene regulation dynamics across weeks

CytoTape enables multiplexed, genetically encoded, spatiotemporally scalable recording of gene regulation dynamics in single cells for up to three weeks with minute-scale resolution.
Medicine
fromwww.theguardian.com
2 months ago

Simple blood test can predict which breast cancer treatment will work best, study finds

A blood test measuring circulating tumour DNA predicts breast cancer treatment response before or within four weeks, enabling alternative therapies and avoiding ineffective drugs.
Science
fromTechCrunch
2 months ago

How AI is helping solve the labor issue in treating rare diseases | TechCrunch

AI multiplies scientific productivity, automating drug discovery tasks to tackle workforce shortages and accelerate development of treatments for thousands of neglected and rare diseases.
Medicine
fromHarvard Gazette
2 months ago

Turns out inherited eye diseases aren't a sure thing - Harvard Gazette

Only a minority of people carrying certain inherited eye-disease gene variants actually develop the disease, exposing strong ascertainment bias and new therapeutic opportunities.
Science
fromMail Online
2 months ago

Scientists use AI to create a virus never seen before

Scientists used AI and gene-assembly tools to create Evo-Φ2147, a novel 11-gene virus designed to kill pathogenic E. coli.
Medicine
fromThe Atlantic
1 month ago

Longevity Medicine Is Being Oversold

Modern longevity medicine is booming due to social-media-driven marketing despite limited placebo-controlled evidence and risks of patient harm.
Medicine
fromIntelligencer
2 months ago

Did AI Alter the Course of This Baby's Life?

A newborn, Jorie, was diagnosed with DeSanto-Shinawi syndrome, a rare, incurable genetic disorder causing neurodevelopmental and physical challenges, with limited treatment options.
Medicine
fromSilicon Canals
1 month ago

Europe Oncology Genomics Tracker Captures Oncologist Perspectives Across Major European Markets - Data Report by DeciBio Consulting LLC - Silicon Canals

Genomic testing adoption for solid tumor oncology is growing across EU-5 with varied country-specific drivers and infrastructure tracked via a survey of 100+ oncologists.
Medicine
fromInsideHook
2 months ago

Scientists Explore Cancer's Connection to Alzheimer's Disease

Certain cancers produce proteins that cross the blood–brain barrier and recruit immune cells, reducing amyloid plaque accumulation and potentially lowering Alzheimer's disease risk.
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