#disease-validation-robins--guze

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fromFast Company
2 days ago

AI is coming for superbugs

Antibiotics are essential for modern medicine, but bacteria are evolving and developing resistance, turning routine infections into life-threatening conditions. A global analysis estimates that antibiotic-resistant infections could cause over 39 million deaths by 2050.
Medicine
fromwww.theguardian.com
2 days ago

Doctors need to stop pretending to have all the answers. I don't know' does not mean I have nothing to offer' | Ranjana Srivastava

The HIV ward, the scene of graphically ill patients when I was training, is long closed because it's no longer needed in most rich countries. When my young neighbour had a stroke, doctors cleverly retrieved the clot suffocating his artery, not just saving his life but also returning it to its full potential.
Medicine
fromenglish.elpais.com
5 days ago

Following the initial trials in Africa of the groundbreaking drug that could put an end to AIDS

On that sunny March morning, in a small health center in Lobamba, a rural area of Eswatini, this 32-year-old sex worker has just become one of the first people in the world to receive lenacapavir, a drug that, administered twice a year, offers nearly 100% protection against HIV.
Medicine
fromwww.npr.org
2 weeks ago

Inside a rare lab that's blazing a bold trail as it hunts for new drugs

Kelly Chibale describes the drug discovery process as a fairy-tale quest, stating, 'It doesn't mean that there aren't surprises or miracles. They do happen, but you have to kiss many frogs before you meet the prince.' This metaphor illustrates the challenges and unpredictability in finding effective medicines.
US news
fromenglish.elpais.com
2 weeks ago

100 experts were unable to agree on whether aging is an illness, or when it begins

The most prevalent human mortality risk factor, aging, seems to still be hidden in the mist, states the article summing up the survey's results that was published in the journal PNAS Nexus.
Health
fromIndependent
6 days ago

Retired urologist faces tribunal over alleged patient care failures and failure to triage hundreds of GP referrals

Aidan O'Brien faces a series of allegations including that he failed to provide good clinical care to 10 patients between 2011 and 2019.
Medicine
fromThe Atlantic
3 weeks ago

I Remember a World Without Vaccines

I am open-minded; I believe in integrative practices, and I agree that the medical establishment can be arrogant and unduly influenced by the pharmaceutical industry, which now funds so much of medical research. But I fully understand Scherer's frustration with his interminable discussions with Kennedy about scientific articles.
Coronavirus
Cancer
fromBusiness Insider
3 weeks ago

Stop ignoring subtle signs of cancer. A doctor explains when to get medical help.

Early cancer symptoms are often subtle and easily missed, including unexplained fatigue, persistent pain, and digestive changes; persistent symptoms lasting over a week warrant medical evaluation.
Medicine
fromThe Atlantic
1 week ago

What Makes a Doctor Excel at Diagnosis?

Gurpreet Dhaliwal exemplifies diagnostic excellence, emphasizing continuous improvement and the belief that mastery in diagnosis is an ongoing journey.
Artificial intelligence
fromwww.npr.org
4 weeks ago

ChatGPT might give you bad medical advice, studies warn

AI chatbots provide medical information to millions daily but often mislead users because people lack training in effectively communicating symptoms to these systems.
fromwww.scientificamerican.com
4 weeks ago

First-of-its-kind vaccine protects children from deadly intestinal infections

In children below the age of five, whose immune systems are still developing, the infections can lead to malnourishment; they cause up to 42,000 deaths annually. Soon there may be a vaccine to protect against these infections. In the Lancet Infectious Diseases last month, scientists shared the results of the first study to evaluate the safety and efficacy of an ETEC-controlling vaccine in a large pediatric population in Gambia.
Public health
fromwww.bbc.com
3 weeks ago

Police probe breast cancer treatment allegations

A report last year found unnecessary surgeries were carried out, cancers were missed and poor standards of care were delivered at the University Hospital of North Durham and Darlington Memorial Hospital. CDDTF said it wanted to support the patients it had let down, including by offering access to psychological support, and to ensure they knew how to make a claim or raise concerns with police.
Cancer
Healthcare
fromHarvard Business Review
4 weeks ago

Healthcare Uses Specialized Language. It Needs Specialized AI, Too.

Healthcare professionals across specialties use inconsistent terminology and communication styles, creating significant translation barriers that impede care coordination and data interoperability.
Public health
fromwww.theguardian.com
1 month ago

Martha's rule may have saved 400 lives so far in England, figures show

Martha's rule, an NHS patient care review system, saved over 400 lives in its first 16 months of operation in England, with helplines receiving over 10,000 calls identifying deteriorating conditions and care improvements.
Online learning
fromeLearning Industry
1 month ago

Teaching Clinicians Measurement-Based Care: Creating Effective Training Programs

Measurement-based care uses repeated standardized assessments to track patient progress objectively, enabling data-driven clinical decisions and treatment adjustments beyond subjective evaluation.
Healthcare
fromZDNET
4 weeks ago

The good, bad, and ugly of AI healthcare, according to a doctor who uses AI

People increasingly use AI for health advice despite its unreliability, driven by declining trust in healthcare institutions and the technology's convenience and accessibility.
Cancer
fromNature
1 month ago

Cancer blood tests are everywhere. Do they really work?

Multi-cancer early detection blood tests show promise but lack regulatory approval and rigorous trial evidence, with initial results indicating limited effectiveness in improving cancer outcomes.
#gene-therapy
Medicine
fromNews Center
4 weeks ago

First Gene Regulation Clinical Trials for Epilepsy Show Promising Results - News Center

Zorevunersen, a gene-regulation therapy, demonstrates safety and effectiveness in reducing seizures and improving developmental outcomes in Dravet syndrome patients by targeting the underlying genetic cause.
Medicine
fromwww.scientificamerican.com
1 month ago

Pioneering gene therapy may treat a deadly seizure disorder

Gene therapy drug zorevunersen significantly reduces seizures in Dravet syndrome patients by targeting the underlying SCN1A gene mutation, offering hope for treatment-resistant cases.
fromNature
1 month ago

The age of animal experiments is waning. Where will science go next?

Last November, the UK government announced a bold plan to phase out animal testing in some areas of research. Animal tests for skin irritation are scheduled for elimination this year, and some studies on dogs should be slashed by 2030. The long-term vision is 'a world where the use of animals in science is eliminated in all but exceptional circumstances'.
Science
Healthcare
fromTheregister
1 month ago

AI doctor's assistant swayed to change scrips - researchers

Healthcare AI systems can be manipulated through prompt injection techniques to bypass safety measures, reveal system instructions, and generate harmful recommendations that persist in patient records.
Public health
fromBusiness Matters
1 month ago

Chronic Disease Prevention Remained Abstract for Too Long - Barbara Mkhitarian Made It Measurable

Digital prevention programs combining nutrition coaching with behavioral psychology achieve average 7 kg weight loss and sustained diabetes risk reduction through evidence-based lifestyle intervention.
Healthcare
fromFuturism
1 month ago

ChatGPT Health Is Staggeringly Bad at Recognizing Life-Threatening Medical Emergencies

ChatGPT Health fails to identify medical emergencies in over half of cases, incorrectly advising patients to stay home instead of seeking immediate hospital care.
Public health
fromArs Technica
1 month ago

Could a vaccine prevent dementia? Shingles shot data only getting stronger.

Shingles vaccines appear to prevent dementia and slow biological aging, with newer vaccines potentially offering even greater protection than previously documented.
Medicine
fromPsychology Today
1 month ago

The Process of Being Diagnosed With a Rare Condition

Sphincter of Oddi dysfunction is a rare condition affecting digestive juice flow that causes severe abdominal pain and is often overlooked in medical diagnosis despite being treatable.
fromArs Technica
1 month ago

Have we leapt into commercial genetic testing without understanding it?

Martschenko's argument is largely that genetic research and data have almost always been used thus far as a justification to further entrench extant social inequalities. But we know the solutions to many of the injustices in our world-trying to lift people out of poverty, for example-and we certainly don't need more genetic research to implement them. Trejo's point is largely that more information is generally better than less.
Science
Mental health
fromPsychology Today
2 months ago

How Biological Beliefs Influence Medication Use

Many antidepressant users endorse biological causes for depression, which associates with prognostic pessimism, longer treatment duration, and reduced attempts to discontinue medication.
Startup companies
fromEntrepreneur
2 months ago

A Breakthrough Medical Technology Is Nearing FDA Review. And a $5B Market.

TriAgenics' Zero3 TBA is a one-minute, minimally invasive preventive treatment that stops wisdom teeth from forming and could create major dental revenue and investor opportunity.
Healthcare
fromwww.theguardian.com
1 month ago

Unbelievably dangerous': experts sound alarm after ChatGPT Health fails to recognise medical emergencies

ChatGPT Health fails to recognize medical emergencies in over half of cases, potentially endangering users by recommending home care instead of emergency department visits.
#ai-in-healthcare
Mental health
fromPsychology Today
2 months ago

How Scientists Finally Learned to Measure the Placebo Effect

Placebo effects can produce real, substantial improvements that make it difficult to determine whether depression treatments produce true therapeutic effects.
fromPsychology Today
1 month ago

How Science Is Learning to Explore Ground Truth

Some clinicians have an uncanny quality. A colleague describes herself and others with this instinct as "witchy"-a capacity to know things about patients they haven't said yet, to follow a stray association to a song lyric or a half-remembered cultural reference and arrive, reliably, at something the patient urgently needed to say but couldn't reach on their own. We see with artificial intelligence these intriguing possibilities for discovery, especially as connections that human beings never would see pop out of apparently unrelated data.
Science
fromwww.bbc.com
2 months ago

Trial launched to 'help spot health risks early'

Public health consultant Dr Ross Keat said supporting people earlier to make small preventative changes would make "a big difference later on". Some 3,500 people in the north of the island within that age bracket are eligible for the checks. The checks will be carried out by two pre-existing nurses that support GP staff and would not replace GP appointments, Keat explained, adding that the cost would be minimal and absorbed by Ramsey Group Practice.
Public health
Science
fromwww.bbc.com
1 month ago

Single vaccine could protect against all coughs, colds and flus, researchers say

A single nasal spray vaccine induces lung macrophage readiness, offering broad protection against viruses, multiple bacteria, and potentially allergies for months.
Medicine
fromenglish.elpais.com
1 month ago

The very long road from a cancer cure' in mice to one in humans

Promising mouse cancer cures often fail to become safe, effective human drugs; premature media claims can create false patient expectations and hinder responsible research progress.
Science
fromMail Online
2 months ago

Scientists use AI to create a virus never seen before

Scientists used AI and gene-assembly tools to create Evo-Φ2147, a novel 11-gene virus designed to kill pathogenic E. coli.
Medicine
fromwww.bbc.com
1 month ago

Multi-cancer blood test missed key goal in NHS trial

Galleri blood test failed to meet the primary endpoint in an NHS trial, though stage-four cancer diagnoses fell by about one-fifth.
Public health
fromScary Mommy
1 month ago

When To Get Cancer Screenings & Whether At-Home Tests Are Legit

Regular, guideline-based cancer screenings enable early detection and improved outcomes amid rising cancer incidence and widespread at-home test misinformation.
Science
fromNature
2 months ago

Developmental convergence and divergence in human stem cell models of autism - Nature

Distinct rare mutations and common genetic variation jointly shape ASD risk, yet convergent molecular pathology and early fetal neurodevelopmental mechanisms can be studied using stem-cell models.
fromwww.scientificamerican.com
2 months ago

Cancer Survival Rates Are the Highest They've Been since the 1970s

On Tuesday the American Cancer Society (ACS) released its annual report on cancer statistics in the U.S., and it offered a rare bit of good news: the proportion of people who were alive at least five years after a cancer diagnosis hit a record high. The report found that, among all cancer patients diagnosed between 2015 and 2021 in the U.S., the survival rate at the five-year mark relative to those who didn't have cancer was 70 percent.
Public health
Healthcare
fromFast Company
2 months ago

AI in healthcare is entering a new era of accountability

Healthcare AI must be trustworthy, explainable, and safe within clinical workflows, not just ambitious or fast.
Science
fromTechCrunch
2 months ago

How AI is helping solve the labor issue in treating rare diseases | TechCrunch

AI multiplies scientific productivity, automating drug discovery tasks to tackle workforce shortages and accelerate development of treatments for thousands of neglected and rare diseases.
Public health
fromwww.theguardian.com
1 month ago

People with obesity 70% more likely to be hospitalised by or die from infection, study finds

Obesity raises the risk of hospitalization and death from infectious diseases by about 70%, linking to roughly one in ten infection-related deaths worldwide.
fromNews Center
1 month ago

Advancing Preventive Care and Cardiovascular Risk Prediction Through Online Tools - News Center

As the Magerstadt Professor of Cardiovascular Epidemiology, Khan studies the epidemiology of risk for heart failure. Using population-based cohorts and large electronic health record data analyses, she performs mechanistic studies that may enhance risk prediction and identify novel therapeutic agents for the prevention and treatment of cardiovascular disease. Khan and her team have developed a tool to predict risk and prevent cardiovascular disease such as heart failure, stroke, arrhythmia, coronary artery disease and many other conditions.
Public health
Medicine
fromNature
2 months ago

The infection enigma: why some people die from typically harmless germs

Genetic mutations in immune-related genes cause inborn errors of immunity that make some people uniquely vulnerable to severe infections and immune disorders.
Public health
fromwww.npr.org
2 months ago

A drop in CDC health alerts leaves doctors 'flying blind'

The CDC issued only six Health Alert Network alerts in 2025, sharply reducing early-warning communications and leaving clinicians and health departments less prepared.
fromScary Mommy
1 month ago

Study Finds Parents Are Right 90% Of The Time When They Suspect Serious Illness

You know that parental instinct when something just isn't quite right with your child? You text your mom friends and gut check with your partner, but you don't think you're being anxious - something might really be wrong. Well, odds are your instinct could be spot-on: A new study published in the JAMA Network found that parents were right 9 times out of 10 when they suspected their child was seriously ill or injured.
Medicine
fromwww.theguardian.com
2 months ago

The sudden rise of scabies: I wouldn't wish it on my worst enemy'

Clothes, toothbrushes, hairbrushes, a teddy Although it should be two teddies, she re-evaluates, quickly. I can hear her trying to quell her panic. A diehard survivalist preparing for catastrophe? Actually, a beleaguered 44-year-old mother recovering from scabies an itchy rash caused by microscopic mites that burrow under human skin. Far-fetched as it sounds, emergency evacuation is exactly what she, her partner and children (six and four) resorted to in November in a desperate bid to beat the bugs.
Public health
Public health
fromwww.bbc.com
2 months ago

NHS cancer gene database to identify patients at risk

NHS England is creating a national register of 120 cancer-linked genes to identify inherited risk and enable targeted screening, monitoring, and personalized treatment.
fromLGBTQ Nation
2 months ago

The amazing cases of 9 people "cured" of HIV each contain clues about a possible cure - LGBTQ Nation

For more than a decade, doctors and researchers have announced that a handful of people around the world have been cured of HIV. Each of these patients has experienced long-term viral control - in some cases for over a decade - without antiretroviral therapy (ART), as AIDSMap notes, though some doctors describe them as being in "remission." While the patients have shown no signs of HIV since stopping ART, at least some uncertainty remains as to whether the virus could eventually rebound in them.
Medicine
fromNews Center
2 months ago

Experimental Drug Shows Promise for Rare Genetic Disorder - News Center

Mucopolysaccharidosis type II (MPS II), or Hunter syndrome, is a rare genetic disorder primarily affecting boys, caused by a deficiency in the enzyme needed to break down sugar molecules. This harmful buildup in cells and tissues impacts multiple body systems, causing frequent infections, organ enlargement and developmental disabilities. Management involves supportive care and enzyme replacement therapy, as there is currently no cure,
Medicine
Public health
fromwww.theguardian.com
2 months ago

Molly never got to hear it': fury as denials finally end on Glasgow hospital infections

A contaminated water system at Glasgow's flagship hospital likely caused serious infections in 84 child cancer patients, contributing to deaths and avoidable harm.
#hepatitis-b
Medicine
fromIntelligencer
2 months ago

Did AI Alter the Course of This Baby's Life?

A newborn, Jorie, was diagnosed with DeSanto-Shinawi syndrome, a rare, incurable genetic disorder causing neurodevelopmental and physical challenges, with limited treatment options.
Public health
fromNature
2 months ago

More than one-third of cancer cases are preventable, massive study finds

Nearly 40% of global new cancer cases in 2022 were attributable to modifiable risk factors, primarily tobacco smoking, infections, and alcohol consumption.
fromenglish.elpais.com
2 months ago

A vaccine to prevent colon cancer shows promising results

Eduardo Vilar-Sanchez has spent more than 10 years pursuing a goal that seemed very distant, but which he now sees as a little closer: to develop a preventive vaccine against cancer. The physician and researcher is leading a study that presented the first promising results of a colon cancer vaccine in a small group of patients suffering from a rare disease that makes them 17 times more likely to develop colon cancer than the general population.
Medicine
fromwww.bbc.com
1 month ago

'Weight-loss jab helped me find my cancer'

The cancer was fastacting, and if I'd left it even six months, the outcome could have been much worse,
Medicine
Medicine
fromwww.bbc.com
1 month ago

AI chatbots pose 'dangerous' risk when giving medical advice, study suggests

AI chatbots provide inconsistent and sometimes inaccurate medical advice that can mislead users and create potential risks for health decision-making.
Medicine
fromPsychology Today
2 months ago

The Compelling History of a Disease Basis for Mental Illness

Psychiatry pursued brain-disease explanations for mental disorders, driven by medicine's historical emphasis on physical disease, despite lack of definitive brain-disease findings this century.
Medicine
fromThe Verge
2 months ago

Google pulls AI overviews for some medical searches

Google gave dangerous medical misinformation: advising pancreatic cancer patients to avoid high-fat foods and providing false liver function test information that could harm patients.
Medicine
fromwww.theguardian.com
2 months ago

Simple blood test can predict which breast cancer treatment will work best, study finds

A blood test measuring circulating tumour DNA predicts breast cancer treatment response before or within four weeks, enabling alternative therapies and avoiding ineffective drugs.
Medicine
fromNews Center
2 months ago

Common Procedure Does Not Prevent Recurrent Pancreatitis, Trial Finds - News Center

ERCP with minor papillotomy does not prevent recurrent acute pancreatitis in adults with pancreas divisum.
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