Cancer
3 months agoOMG science
New study offers clues into genetics of X chromosome loss
Identified genetic variants can potentially predict mosaic loss of chromosome X (mLOX) in women, affecting blood cell abnormalities and raising the risk of cancer.
Genetic variants near autoimmune and cancer-related genes influence the development of mLOX, with particular focus on the FBXO10 gene and X chromosome copies.
Association of mLOX with various diseases, including leukemia and pneumonia susceptibility, prompts further exploration of genetic interactions and disease risks. [ more ]