Focal white matter lesions accumulate with age in the central nervous system and, in neurodegenerative conditions, their number correlates with cognitive and physical impairment. Multiple sclerosis is a demyelinating disorder characterized by white matter demyelinating lesions, while grey matter microgliosis and synaptic loss lead to irreversible neurodegeneration, thought to be the dominant mechanism underlying disability progression.
Tracy O'Connor Pennuto, the federal prison system's only forensic neuropsychologist, testified that Jeffries was logical, 'jovial,' and often funny during two days of testing last year.
Over the past six years, I've had the privilege of caring for patients with varying degrees of cognitive impairment. As a medical cannabis doctor, I often visit these patients in memory care units, seeing these once self-sufficient individuals, their personas now diminished, no longer able to care for themselves. They become angry and anxious as they confront the fact that their minds, their memories, what made them who they were, recollections of all that they have lived through and accomplished, are slipping away from them.
Studies suggest nearly 60 percent of people with OSA experience some degree of cognitive impairment, including difficulties with attention, working memory, and episodic memory. Mood disorders such as depression and anxiety are also more common. Over time, untreated sleep apnea has been linked to declines in concentration, executive function, and long-term memory. So what's actually happening inside the brain while someone with undiagnosed sleep apnea sleeps?
Recent studies conclude that high glucose levels from sugar impacts your memory and impair cognition. In fact, individuals with diabetes, a condition that causes elevated high blood-sugar levels, are known to increase stress and have a higher risk of developing Alzheimer's disease, a form of dementia. It seems that the brain in type II diabetes, just like the body, has difficulty utilizing sugar for energy and this can lead to slower processing when it comes to memory retrieval.