7 Big Questions About Cancer, AnsweredCancer understanding has evolved to include not just genetic mutations but also epigenetic changes that influence gene expression.
CDK5-cyclin B1 regulates mitotic fidelity - NatureCDK5 is essential for mitotic fidelity, acting alongside CDK1 with cyclin B1 as a crucial partner.
Cells poised to divide can delay their commitment to proliferateCells in a 'primed' G1 state can delay or reverse progression to division.