#bioinformatics

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fromNature
3 days ago

Daily briefing: Chronic pain linked to small cluster of brain cells

Researchers have launched a search engine that can quickly sift through the staggering volumes of biological data housed in public repositories. The team integrated data from seven publicly funded data archives, creating 18.8million unique DNA and RNA sequence sets and 210billion amino-acid sequence sets that users can search through using text prompts. The search engine, called MetaGraph, can also uncover genetic patterns hidden deep within expansive sequencing data sets without needing those patterns to be explicitly annotated in advance.
OMG science
fromNature
4 days ago

'Google for DNA' brings order to biology's big data

"It's a huge achievement," says Rayan Chikhi, a biocomputing researcher at the Pasteur Institute in Paris. "They set a new standard" for analysing raw biological data - including DNA, RNA and protein sequences - from databases that can contain millions of billions of DNA letters, amounting to 'petabases' of information, more entries than all the webpages in Google's vast index.
Science
fromNature
1 month ago

Beyond AlphaFold: how AI is decoding the grammar of the genome

AI models like Evo and regLM can generate new sequences of mobile DNA and predict regulatory activity in human cell lines based on prompts.
Artificial intelligence
Science
fromInfoQ
3 months ago

Google DeepMind Unveils AlphaGenome: A Unified AI Model for High-Resolution Genome Interpretation

AlphaGenome is a new AI model that predicts the effect of genetic variants on gene regulation across the genome.
fromNature
3 months ago

'We couldn't live without it': the UCSC Genome Browser turns 25

The website took on a life of its own, showcasing the ongoing evolution and impact of the UCSC Genome Browser, vital for genomic research.
Science
SF parents
fromNature
4 months ago

Reply to: False positives in study of memory-related gene expression - Nature

Interdisciplinary collaboration is crucial for modern biological research.
Bioinformatics plays a vital role in uncovering molecular mechanisms.
Scala
fromHackernoon
4 months ago

Baseline Models for Single-Cell RNA-seq Dimensionality Reduction | HackerNoon

scVI is an advanced model for single-cell analysis, effectively addressing challenges like count data and batch effects.
OMG science
fromNature
5 months ago

Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs - Nature

Collaboration across different research specialties is key to advancing cancer biology and therapeutic strategies.
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