#autoimmunity

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#peripheral-immune-tolerance #regulatory-t-cells #t-cells #immunology #nobel-prize-2025 #2025-nobel-prize
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Medicine
fromWIRED
1 week ago

Scientist Who Was Offline 'Living His Best Life' Stunned by Nobel Prize Win

Fred Ramsdell, Mary E. Brunkow and Shimon Sakaguchi won the 2025 Nobel Prize for discoveries revealing peripheral immune tolerance mechanisms.
Medicine
fromArs Technica
2 weeks ago

Discovery of cells that keep immune responses in check wins medicine Nobel Prize

Foxp3 is the master regulator of regulatory T cells; mutations cause severe autoimmune disease in mice and humans (scurfy, IPEX).
fromsfist.com
2 weeks ago

San Francisco-Based Scientist Wins Nobel Prize for Medicine

"Their discoveries have been decisive for our understanding of how the immune system functions and why we do not all develop serious autoimmune diseases," said Olle Kampe, chair of the Nobel Committee, in a statement.
Medicine
Medicine
fromwww.theguardian.com
2 weeks ago

Nobel prize in medicine awarded to scientists for immune system research

Mary E Brunkow, Fred Ramsdell and Shimon Sakaguchi won the 2025 Nobel Prize in Physiology or Medicine for discoveries on peripheral immune tolerance.
Medicine
fromwww.sandiegouniontribune.com
2 weeks ago

New study builds evidence of immune system's role in ALS

T cells in ALS patients show altered behavior and a shifted inflammatory/anti-inflammatory balance linked to C9orf72, indicating possible autoimmune involvement and treatment targets.
fromNature
4 months ago

Developmental trajectory and evolutionary origin of thymic mimetic cells - Nature

The emergence of somatic diversification of antigen receptor genes necessitated a reorganization of immune systems to prevent fatal autoimmunity linked to random receptor specificities.
MMA
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