San Francisco-Based Scientist Wins Nobel Prize for Medicine
"Their discoveries have been decisive for our understanding of how the immune system functions and why we do not all develop serious autoimmune diseases," said Olle Kampe, chair of the Nobel Committee, in a statement.
New study builds evidence of immune system's role in ALS
T cells in ALS patients show altered behavior and a shifted inflammatory/anti-inflammatory balance linked to C9orf72, indicating possible autoimmune involvement and treatment targets.
Developmental trajectory and evolutionary origin of thymic mimetic cells - Nature
The emergence of somatic diversification of antigen receptor genes necessitated a reorganization of immune systems to prevent fatal autoimmunity linked to random receptor specificities.