Why your morning coffee stops working after a few weeks and how to reset your tolerance - Silicon Canals
Briefly

Why your morning coffee stops working after a few weeks and how to reset your tolerance - Silicon Canals
"When you drink coffee, caffeine blocks adenosine receptors in your brain. Adenosine is the chemical that builds up throughout the day and makes you feel tired. Block those receptors, and suddenly you feel alert and focused. But here's where it gets interesting. Your brain notices this pattern and essentially says, "Oh, we're doing this every day now? Cool, let me adjust.""
"It starts producing more adenosine receptors to compensate for all the ones being blocked by caffeine. Think of it like your brain building more parking spots because the usual ones are always taken. This process is called tolerance, and it happens surprisingly quickly. Within just a few weeks of regular coffee consumption, your brain has already started adapting. Those extra adenosine receptors mean you need more caffeine to achieve the same effect. What used to take one cup now takes two, then three, then four."
Regular coffee consumption causes the brain to produce more adenosine receptors, diminishing caffeine's ability to block them and sustain alertness. Adenosine accumulates during the day and signals tiredness; caffeine temporarily blocks those receptors to create wakefulness. The brain compensates by increasing receptor numbers, producing tolerance within weeks. Tolerance raises the caffeine amount needed for the same effect, prompting higher intake without restored alertness. This escalation can lead to daily dependence and persistent sluggishness despite multiple cups. Breaking the cycle requires reducing or pausing caffeine to allow receptor levels and sensitivity to normalize.
Read at Silicon Canals
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