"Nine in 10 Alzheimer's cases would not develop without the contribution of a single gene, nor would almost half of all dementia cases, researchers find. Alzheimer's is the most common form of dementia, making up 60 to 80 per cent of the almost one million dementia cases in the UK. A complex mix of factors including age, lifestyle choices such as smoking, and environmental factors like air pollution and genes, can all contribute to the risk of developing Alzheimer's disease."
"One gene called APOE has long been known to increase the risk of Alzheimer's disease. But scientists have found that without a certain variant of this gene, most cases would not occur, making it a powerful target for drug development, according to researchers at University College London (UCL) and the University of Eastern Finland. A mix of factors including age, lifestyle, environment and genes can all influence a person's risk of Alzheimer's disease (Getty/iStock)"
The Independent deploys journalists across issues including reproductive rights, climate change and Big Tech, produces documentaries like 'The A Word', avoids paywalls and relies on donations to fund reporting. Nine in ten Alzheimer's cases would not develop without the contribution of a single gene, and almost half of dementia cases depend on that gene's influence. Alzheimer's constitutes 60–80 percent of nearly one million dementia cases in the UK. Risk factors include age, smoking and environmental pollution as well as genetics. The APOE gene has common types 2, 3 and 4, with the 4 variant linked to increased dementia risk and certain variants presenting targets for drug development.
Read at www.independent.co.uk
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