"We've created a small molecule chemical which gets in your body very well. It can mimic the effects of the peptide and can be taken more conveniently any time of day without any food or water restrictions."
"The decision to approve Foundayo took 50 days, the agency said, and is the fastest for a brand-new kind of drug since 2002."
"Unlike Foundayo, the Wegovy pill has to be taken on an empty stomach and the patient has to fast for 30 minutes in order for it to work."
The FDA has approved Eli Lilly's Foundayo, a once-daily GLP-1 pill for obesity, competing with Novo Nordisk's Wegovy. Foundayo's active ingredient, orforglipron, is easier to absorb than peptides, allowing for more convenient dosing without food restrictions. The approval process was expedited, taking only 50 days. While the pill format may appeal to patients, high costs and insurance limitations pose significant barriers to access. Foundayo's convenience may make it a preferable option for some patients compared to Wegovy, which requires fasting and has more stringent intake conditions.
Read at www.npr.org
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