Scientists have discovered gepotidacin, an effective new antibiotic for gonorrhoea, as detailed in The Lancet. This development is critical due to the alarming rise in gonorrhoea cases in the UK, with over 85,000 diagnoses in 2023 alone. Gepotidacin not only matches the effectiveness of existing treatments but also addresses drug-resistant strains that have emerged. The trial involved 628 patients and revealed mild side effects. As resistance to current antibiotics increases, new treatments are essential, with gepotidacin and another candidate, zoliflodacin, showing promise. A vaccine is also under consideration to combat this STI.
"Gepotidacin can treat and clear gonorrhoea just as effectively as current antibiotics while tackling emerging drug-resistant strains, signaling a major breakthrough against the STI."
"The bacterium causing gonorrhoea has developed resistance to most antibiotics, raising significant concerns about future treatability. New drugs like gepotidacin and zoliflodacin are urgently needed."
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