"That's because the deeply peculiar snippets appear to be setting up something much more unusual than even the elevator pitch suggests. Plur1bus, as it's styled in its logo, is about an author who also happens to be "the world's most miserable person" (played by Rhea Seehorn of Better Call Saul), attempting to save her fellow humans from a virus that's causing uncontrollable optimism and happiness."
"It's such a splendid premise, with Seehorn's Carol Sturka apparently immune to whatever is happening to the rest of the world-and she's well-placed to be, given her previously established misanthropy. While we know very little about the show just yet, Entertainment Weekly was able to discover that Carol was the author of historical romance novels, which she describes as "mindless crap.""
Plur1bus centers on Carol Sturka, a misanthropic historical-romance author who appears immune to a mysterious virus that causes uncontrollable optimism and contentedness. The infection spreads through an Albuquerque population, leaving all but one person transformed into excessively positive versions of themselves. Carol's immunity positions her to attempt saving others while confronting the discomfort of pervasive happiness. The series relocates familiar Better Call Saul actors to a distinct sci-fi premise rather than extending the Breaking Bad universe. The title uses a "1" in place of an "i"; "pluribus" derives from Latin for "many." Creators promise unexpected complications and surprising twists.
Read at Kotaku
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