"Professor Spear told the Daily Mail that midlife fatigue is best understood as a 'mismatch between biology and demand'. She says: 'Our bodies are still perfectly capable of producing energy, but they do so under different conditions than in earlier adulthood, while the demands placed on that energy often peak.' However, the good news is that these biological imbalances that sap our energy are only temporary. In fact, many people may even experience a second wind as they get older, according to the expert."
"Looking back on your 20s, it might have felt like everything was just a little bit easier for your body. You could go to sleep later, stay out longer, exercise more sporadically, and still stay in relatively good shape. 'In our 20s, the body is biologically very forgiving,' explains Professor Spear. 'Muscle repair is faster, inflammatory responses are shorter-lived, and energy production at a cellular level is both efficient and plentiful.'"
People commonly experience their most tiring decade in their 40s because small biological changes converge while life, work, and parenting demands often peak. Midlife fatigue reflects a mismatch between biological energy conditions and external demands. Cellular energy production remains possible but functions under different conditions than earlier adulthood, reducing spare capacity. These biological imbalances are generally temporary, and many individuals experience renewed energy later in life. In the 20s, muscle repair is faster, inflammatory responses are shorter-lived, and mitochondria generate energy more efficiently with fewer inflammatory by-products, so late nights and sporadic exercise have milder consequences.
Read at Mail Online
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