"There are many acronyms you might find on the packaging of so-called longevity supplements, promoted by influencers for their ability to repair DNA and assist in anti-ageing. NRC (nicotinamide riboside chloride) and NMN (nicotinamide mononucleotide) are two of them both precursors or building blocks for NAD (nicotinamide adenine dinucleotide), a naturally occurring molecule in the body. Trimethylglycine (TMG) is another and is sometimes added to support other ingredients."
"Packaged together, these ingredients are supposed to boost daily vitality and improve cellular health, according to their promoters. But is there any evidence to support these claims? What are longevity supplements? While some longevity supplements contain multiple ingredients in one tablet, others promote stacking that is, buying different products and ingredients and taking them together for an optimum longevity boost."
Many longevity supplements contain NAD precursors such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), sometimes with trimethylglycine (TMG). These ingredients are presented as building blocks for nicotinamide adenine dinucleotide (NAD). NAD participates in energy production, DNA repair and numerous biochemical reactions. The body can synthesise NAD de novo or recycle it from other compounds. Some proponents suggest supplying precursors increases NAD production. NAD levels are reported to decline with age, which motivates anti-ageing claims. However, a single compound among thousands is unlikely to determine ageing, and declining NAD does not prove it causes ageing.
Read at www.theguardian.com
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