"So the largest study was from 2024; that came out of Sweden. The researchers looked at nearly 2.5 million people who were born between 1995 and 2019, and among those people rates of autism diagnoses were about 0.09 percentage points higher for the people who took Tylenol during pregnancy versus those who didn't. But the effects disappeared once they controlled for genetic factors through what's called a sibling-control analysis."
"Allison Parshall: So a handful of studies have shown a link between Tylenol use in pregnancy and autism diagnoses, but importantly that increase in risk has been relatively small and quite inconsistent across studies. So the largest study was from 2024; that came out of Sweden. The researchers looked at nearly 2.5 million people who were born between 1995 and 2019,"
A handful of studies have reported associations between prenatal acetaminophen (Tylenol) use and autism diagnoses, but observed risk increases have been small and inconsistent. The largest 2024 Swedish study of nearly 2.5 million births found about a 0.09 percentage-point higher autism diagnosis rate among those exposed prenatally, but sibling-control analyses that account for shared genetics eliminated the effect. Sibling comparisons examined pairs where a parent used acetaminophen in one pregnancy but not another, indicating genetic or familial confounding rather than a clear causal link. Overall evidence suggests any association is weak and potentially explained by genetic or familial factors.
Read at www.scientificamerican.com
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