Editorial Expression of Concern: The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM
Briefly

"Editorial Expression of Concern Published: 21 January 2026 J. Sayos1, C. Wu1, M. Morra1, N. Wang1, X. Zhang1, D. Allen1, S. van Schaik1, L. Notarangelo2, R. Geha3, M. G. Roncarolo4, H. Oettgen3, J. E. De Vries5, G. Aversa5 & C. Terhorst1 Nature (2026)Cite this article Addendum to: Nature https://doi.org/10.1038/26683 Published online 1 October 1998"
"The Editors would like to alert the readers that concerns have been raised regarding the PCR gel presented in Fig. 4a. Specifically, the bottom halves of lanes B3 and B1 in Fig. 4a appear highly similar."
An Editorial Expression of Concern was published on 21 January 2026 regarding a PCR gel image in Fig. 4a. Concerns identify that the bottom halves of lanes B3 and B1 appear highly similar. The similarity raises questions about image integrity and potential duplication in the gel presentation. The notice references the original 1998 publication (DOI: 10.1038/26683) and specifies the figure and lanes at issue. The identified similarity may warrant further investigation or clarification to determine whether the image reflects an inadvertent error or deliberate manipulation.
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