Research Suggests GLP-1 Drugs Could Be for the Long Haul

"Last month, the World Health Organization updated its guidelines for GLP-1 drugs like Ozempic and Wegovy. Among the guidelines were several conditional recommendations, as well as a perspective that took the long view, temporally speaking. "Our new guidance recognizes that obesity is a chronic disease that can be treated with comprehensive and lifelong care," Dr. Tedros Adhanom Ghebreyesus, the organization's Director-General, said in a statement.That "lifelong" isn't said lightly."

"As Dani Blum noted in a recent New York Times article, a growing amount of medical research suggests that if you're taking GLP-1 drugs now, you're going to be in it for the long haul lest you risk regaining some or all of the weight that you lost along the way.There's already been some anecdotal evidence of this - including, as Blum points out, Oprah Winfrey's comments about her own GLP-1 usage."

The World Health Organization updated guidelines for GLP-1 drugs, offering conditional recommendations and endorsing long-term management of obesity as a chronic disease. GLP-1 medications can produce weight loss, but cessation often triggers rapid weight regain and reversal of beneficial cardiometabolic markers. Anecdotal reports and research support the possibility that GLP-1 treatment may need to continue indefinitely for many patients. Individuals considering stopping should prepare a plan to maintain weight loss. Emerging oral GLP-1 formulations and other factors may change management, but multiple considerations remain important.

Read at InsideHook