"Taking paracetamol while pregnant is safe and there's no evidence it raises the risk of autism, ADHD and developmental issues in children, say experts behind a major new review. Pregnant women "should feel reassured" by the findings, say, which contradict controversial claims from US President Donald Trump last year that paracetamol "is no good" and pregnant women should "fight like hell" not to take it. His views were criticised at the time by medical organisations worldwide."
"Published in The Lancet Obstetrics, Gynaecology & Women's Health, it looked at 43 of the most robust studies into paracetamol use during pregnancy, involving hundreds of thousands of women, particularly those comparing pregnancies where the mother had taken the drug to pregnancies where she hadn't. The researchers say using these high-quality studies of siblings means they can dismiss other factors such as different genes and family environments, which makes their review "gold-standard"."
A synthesis of 43 high-quality studies involving hundreds of thousands of pregnant women used sibling-comparison designs to control for genetic and familial confounders. Studies with low risk of bias and follow-up beyond five years were included to assess long-term outcomes. The pooled analysis found no association between prenatal paracetamol (acetaminophen) exposure and increased risk of autism, ADHD, or other developmental disorders in children. Conclusions indicate that paracetamol does not raise these risks and that pregnant women can be reassured about its safety. Some US health authorities continue to express caution despite the absence of evidence for harm.
Read at www.bbc.com
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