
""This study addresses an urgent need to define the differing long COVID trajectories," said senior author Bruce Levy of Mass General Brigham's Department of Medicine and Division of Pulmonary and Critical Care Medicine, and the Hersey Professor of the Theory and Practice of Physic at Harvard Medical School. "Our findings will help determine what resources are needed for clinical and public health support of individuals with long COVID and will also inform efforts to understand long COVID's biological basis.""
""To identify long COVID trajectories, the researchers followed 3,659 adult participants in the RECOVER initiative who first contracted SARS-CoV-2 during the Omicron variant era, after Dec. 1, 2021. The participants completed a comprehensive symptom questionnaire in three-month intervals up to 15 months post-infection to track changes over time. Then, the researchers identified patients with long COVID using the long COVID research index, a symptom-based tool that was previously developed by Mass General Brigham researchers.""
Millions of patients have developed long COVID, a chronic condition that involves symptoms such as fatigue, brain fog, dizziness, and palpitations that persist for at least three months after infection. Eight different trajectories of long COVID were identified, varying by severity, duration, and whether symptoms improved, worsened, or persisted. A cohort of 3,659 adults who contracted SARS-CoV-2 during the Omicron era (after Dec. 1, 2021) completed comprehensive symptom questionnaires at three-month intervals for up to 15 months post-infection to track symptom changes over time. Patients with long COVID were identified using a symptom-based long COVID research index developed by Mass General Brigham researchers. Overall, 10.3 percent of patients had long COVID symptoms three months after infection, and among those, 81 percent continued to experience persistent or intermittent symptoms.
Read at Harvard Gazette
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