Researchers have pioneered a method for creating human-animal chimaeras by injecting human cells directly into the amniotic fluid of pregnant mice. This technique resulted in offspring exhibiting human cells in multiple organs, including the liver, intestines, and brain. However, to maximize its effectiveness, it is necessary to improve the proportion of human cells that develop in these organs. The ultimate goal is to create viable human organs for transplantation through enhanced understanding of human tissue growth in animal models. This breakthrough was discussed at an international stem cell research meeting.
To develop more effective human-animal chimaeras, researchers successfully injected human cells into pregnant mice's amniotic fluid, yielding baby mice with human cells in vital organs.
Using this innovative technique, researchers hope to improve the integration and survival rate of human cells within animal organs for transplantation studies.
#human-animal-chimaeras #stem-cell-research #organ-transplantation #biomedical-innovation #research-techniques
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