The San Francisco 49ers finished 6-11 last season and are listed at +160 on ESPN BET to win the NFC West in 2025. The Los Angeles Rams are +175 after reaching the divisional round last season, and both teams are 20-1 among the top 10 to win Super Bowl LX. Arizona and Seattle have win totals posted at 8.5, while San Francisco is at 10.5 and the Rams at 9.5. Recommended bets include Cardinals UNDER 8.5 wins (+105) due to late-season collapse and turnover struggles, and Seahawks OVER 8.5 wins (+130) because Sam Darnold fits Klint Kubiak’s scheme and the defense could improve.
The San Francisco 49ers went 6-11 and missed the playoffs last season but are +160 at ESPN BET to win the NFC West in 2025. Right there with them are the Los Angeles Rams (+175), who last season advanced to the divisional round of the playoffs. At 20-1, the 49ers and Rams are among the top 10 teams with the best odds to win Super Bowl LX.
Cardinals UNDER 8.5 wins (+105) Maldonado: The Cardinals are one of those teams I constantly forget about, and maybe that's the point. They were 6-4 going into their bye last season but then cratered and won just two games the rest of the way. That wasn't a fluke. It's been their M.O. for years. Kyler Murray stayed healthy but couldn't push the ball downfield, and even though the defense added pieces, it still still struggled to produce turnovers.
Seahawks OVER 8.5 wins (+130) Matt Bowen: Sam Darnold has the mobility and arm strength to play a productive role under new coordinator Klint Kubiak's system that sets up the quarterback on play-action, boot and shot plays. Yes, The Seahawks need to take the ball away more this season (only 18 forced turnovers in '24), but they have the scheme to hit the quarterback and the secondary talent to see a boost in on-the-ball production.
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