"President Trump was surrounded by key medical officials in his administration including the Secretary of Health and Human Services on September 22, 2025, when he implied that taking acetaminophen (Tylenol) during pregnancy causes autism: "... acetaminophen which is basically commonly known as Tylenol during pregnancy, can be associated with a very increased risk of autism."[1] Additionally, the president suggested a new potential "treatment" for autism:"
"This does seem quite similar to the president's statement that leucovorin (vitamin B9) "reflects potential benefits in reducing some autism symptoms." The current paucity of strong evidence for the benefits of this drug is reflected in a 2025 review of leucovorin treatment for autism indicating that studies were based on "small sample sizes and modest mean differences" and noting, "folinic acid administration has the potential"
A presidential statement linked prenatal acetaminophen (Tylenol) use to an increased risk of autism and announced an updated drug label suggesting potential symptom reduction. The drug cited is leucovorin (folinic acid), a prescription form of folate (vitamin B9). B‑vitamin therapies have a long history as proposed autism treatments, with early reports noting that vitamin B6 helped some symptoms in some patients. Recent reviews find limited, low‑quality evidence for leucovorin, characterized by small sample sizes and modest mean differences. Identifying risk factors is not equivalent to proving causes, and rigorous studies are needed before declaring definitive causes or treatments.
Read at Psychology Today
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