"Drugs that limit the activity of cells called neutrophils could make heart attacks less severe without compromising the immune system."
"Manipulating the activity of neutrophils, a type of immune cell, could provide a way to reduce the severity of heart attacks."
Drugs that limit the activity of neutrophils could reduce the severity of heart attacks without compromising immune function. Manipulating neutrophil activity offers a potential strategy to decrease cardiac tissue damage during myocardial infarction. Pharmacological modulation aims to reduce harmful neutrophil-driven inflammation while retaining protective antimicrobial roles. Targeting neutrophil activation pathways could balance lowering ischemic injury with maintaining host defence. Clinical development will require careful evaluation of safety, dosing, and effects on infection risk to ensure therapeutic benefit without unintended immune suppression.
Read at Nature
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