"Women who want to to get pregnant should refrain from using cannabis. This is the conclusion of a new study that examined the influence of the substance, and its active ingredient THC in particular, on female fertility and artificial insemination. Researchers found that cannabis can negatively affect both because it disrupts the development and stability of the egg cell. During in vitro fertilization (IVF), egg and sperm cells are brought together in a laboratory."
"The authors investigated both the effects of THC on isolated human eggs in the laboratory and the IVF results of patients with detectable THC in their follicular fluid. This is the fluid in the ovary that surrounds the egg, where detectable THC means that the woman consumed cannabis before or during the IVF cycle, and that the THC reached the egg cell environment."
Cannabis use before or during IVF introduces THC into the follicular fluid that surrounds the egg, exposing the egg cell environment to the compound. THC disrupts egg development and stability, leading to lower rates of euploid embryos and reducing the chance of genetically healthy embryos and successful pregnancy. Among 1,059 IVF patients, 62 had detectable THC in follicular fluid; THC-positive patients showed significantly lower euploid embryo rates. THC exposure was associated with adverse outcomes in egg maturation, fertilization, blastocyst development, increased cell-division errors, and elevated aneuploidy risk linked to miscarriages.
Read at www.dw.com
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