"This is a huge finding. Many more people will have hope that they can have biological children. It's great to see for the patients for whom we already have tissue banked."
"Treatments such as chemotherapy and radiotherapy can be life-saving for childhood cancer and sickle cell patients but can also leave them infertile."
"The immature testes contain spermatogonial stem cells—the precursors of sperm—and sertoli cells, essential nurse cells that support and nourish developing sperm."
"We told patients' families we couldn't guarantee that the fertility restoration would be successful."
A 27-year-old man produced sperm after receiving a transplant of cryopreserved testicular tissue frozen at age 10, prior to chemotherapy for sickle cell disease. This marks the first successful restoration of sperm production from prepubertal testicular tissue in an adult. The procedure offers hope for many who face infertility due to cancer treatments. The clinic began banking testicular tissue in 2002, and advancements in this field have led to successful outcomes for patients now seeking to start families.
Read at www.theguardian.com
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