
"This is one of the first studies to show that even small differences in blood pressure at age seven - whether systolic or diastolic - can have long-term consequences,"
"We were surprised by the timing - that blood pressure at such an early age is linked with outcomes up to 50 years later."
Data from the Collaborative Perinatal Project, which followed more than 30,000 children born between 1959 and 1965, were analyzed for childhood blood pressure and adult cardiovascular outcomes. Elevated systolic and diastolic blood pressure at age seven was associated with a 40–50% greater risk of premature cardiovascular death in adulthood. The increased risk persisted independent of body mass index, indicating elevated blood pressure alone confers long-term risk. A sibling analysis of 150 pairs that controlled for shared genetics and home environment showed siblings with higher systolic blood pressure had higher cardiovascular mortality risk. Findings underscore the need for earlier cardiovascular screening and awareness.
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