Almost 2bn to be affected by metabolic liver disease by 2050, study suggests

"The global prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) has surged to 1.3 billion people, marking a 143% increase over the past three decades. By 2050, projections indicate that this number could rise to 1.8 billion, primarily due to rising obesity and blood sugar levels."

"High blood sugar is identified as the leading driver of MASLD-related health issues globally, followed by high BMI and smoking, which are closely linked to type 2 diabetes and obesity."

"The prevalence of MASLD is notably higher in men than women, with the most affected age group being older adults aged 80 to 84, while younger individuals aged 35 to 39 in men and 55 to 59 in women represent the largest number of cases."

Metabolic dysfunction-associated steatotic liver disease (MASLD) is rapidly increasing, with 1.3 billion people currently affected. This represents a 143% increase since 1990. The prevalence is expected to rise to 1.8 billion by 2050, driven by global population growth and lifestyle changes. The condition is more common in men and older adults, with high blood sugar being the leading cause. Regions like North Africa and the Middle East show disproportionately high rates, while the UK has seen a 33% increase in prevalence since 1990.

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